⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ethylene Glycol SCHEMBL28725543 | 0.93 | ALDH1A1 (0.48) | — | |
| SCHEMBL31607435 | 0.93 | CES2 (0.48) | — | |
| SCHEMBL1921248 | 0.87 | ALDH1A1 (0.50) | — | |
| Ethylene Glycol SCHEMBL28725533 | 0.87 | ALDH1A1 (0.46) | — | |
| Ethylene Glycol SCHEMBL28725531 | 0.85 | CES2 (0.47) | — | |
| SCHEMBL26838518 | 0.84 | ALDH1A1 (0.42) | — | |
| SCHEMBL18660230 | 0.84 | ALDH1A1 (0.47) | — | |
| SCHEMBL101044 | 0.84 | — | — | |
| SCHEMBL18996625 | 0.83 | CES2 (0.54) | — | |
| SCHEMBL8016543 | 0.83 | CES2 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354781-A | Peptide inhibitors of interleukin-23 receptor | 西兰制药公司 | 2024-07-16 | — | — | CN | disclosed |
| US-9920365-B2 | Functionalized cyanine dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2018-03-20 | — | — | US | disclosed |
| WO-2017059411-A9 | INHIBITORS OF MENAQUINONE BIOSYNTHESIS | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2017-08-31 | — | — | WO | disclosed |
| US-20170136104-A1 | GLYCOPEGYLATED FACTOR IX | NOVO NORDISK AS (DK) | 2017-05-18 | — | — | US | disclosed |
| WO-2017041139-A1 | LYMPH DIRECTING PRODRUGS | MONASH UNIVERSITY (AU) | 2017-03-16 | — | — | WO | disclosed |
| US-20160361427-A1 | Glycopegylated Factor IX | NOVO NORDISK AS (DK) | 2016-12-15 | — | — | US | disclosed |
| US-20160184412-A1 | Glycopegylated Factor IX | NOVO NORDISK AS (DK) | 2016-06-30 | — | — | US | disclosed |
| US-20160158319-A1 | REMODELING AND GLYCOPEGYLATION OF FIBROBLAST GROWTH FACTOR (FGF) | NOVO NORDISK A/S (DK) | 2016-06-09 | — | — | US | disclosed |
| US-20150344950-A1 | Functionalized Cyanine Dyes (PEG) | PACIFIC BIOSCIENCES OF CALIFORNIA, INC. (US) | 2015-12-03 | — | — | US | disclosed |
| US-9200049-B2 | Remodeling and glycopegylation of fibroblast growth factor (FGF) | NOVO NORDISK A/S (DK) | 2015-12-01 | — | — | US | disclosed |
| US-20080176790-A1 | Remodeling and Glycopegylation of Fibroblast Growth Factor (Fgf) | 89BIO, INC. | 2008-07-24 | — | — | US | disclosed |
| US-5512577-A | Bicyclic hexahydroaporphine and 1-benzyloctahydroisoquinoline therapeutic compositions and processes for utilizing said compositions | CREIGHTON UNIVERSITY (US) | 1996-04-30 | — | — | US | disclosed |
| EP-0666855-A1 | 4-QUINOLINYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY. | JANSSEN PHARMACEUTICA NV (BE) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010164-A1 | 4-QUINOLINYL DERIVATIVES WITH ANTI-HELICOBACTER ACTIVITY | JANSSEN PHARMACEUTICA N.V. (BE) | 1994-05-11 | — | — | WO | disclosed |
| US-4443475-A | ANTIARRHYTHMIA AGENTS, ANTIDEPRESSANTS | CAVAZZA CLAUDIO (IT) | 1984-04-17 | — | — | US | disclosed |
| US-4234619-A | Decholesterolized and defatted egg powder and method for producing same | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1980-11-18 | — | — | US | disclosed |
| US-4153778-A | POLYOXYBUTYLENE GLYCOL OR POLYCAPROLACTONE CAPPED WITH A DIISOCYANATE, A DI- OR TRI-METHYLOL CARBOXYLIC ACID, AND A HYDROXY-ALKYL ACR | UNION CARBIDE CORPORATION (US) | 1979-05-08 | — | — | US | disclosed |
| US-3978134-A | INSECTICIDE | SANDOZ LTD. (CH) | 1976-08-31 | — | — | US | disclosed |
| US-3968235-A | Composition and method for combating insects with alkylenedioxyphenyl derivatives | SANDOZ LTD. (CH) | 1976-07-06 | — | — | US | disclosed |
| US-3933804-A | Insecticidal 1,3-benzodioxol derivatives | SANDOZ LTD., (SANDOZ AG) (CH) | 1976-01-20 | — | — | US | disclosed |