Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PRTN3 | P24158 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2734650 | 0.94 | KMT2A (0.46) | KMT2ALMNACA2CA1FAAH | |
| SCHEMBL2734668 | 0.92 | CA2 (0.46) | KMT2ALMNACA2CA1FAAH | |
| SCHEMBL2733253 | 0.92 | CA2 (0.46) | KMT2ALMNACA2CA1FAAH | |
| SCHEMBL2734251 | 0.92 | CA2 (0.46) | KMT2ALMNACA2CA1FAAH | |
| SCHEMBL1149170 | 0.88 | CA2 (0.50) | KMT2ALMNACA2CA1FAAH | |
| SCHEMBL7388716 | 0.82 | ALDH1A1 (0.47) | KMT2ALMNAALDH1A1MEN1HTT | |
| SCHEMBL15686580 | 0.82 | CA2 (0.65) | KMT2ACA2CA1FAAHPRSS1 | |
| SCHEMBL7391786 | 0.81 | USP2 (0.39) | KMT2ALMNACA2CA1CA9 | |
| SCHEMBL8778805 | 0.80 | ALDH1A1 (0.49) | KMT2ACA2CA1FAAHPRSS1 | |
| SCHEMBL23497326 | 0.79 | CA2 (0.60) | KMT2ALMNACA2CA1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979818-B1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | MITSUBISHI PHARMA CORP (JP) | 2003-02-19 | — | — | EP | disclosed |
| EP-0979818-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 2000-02-16 | — | — | EP | disclosed |
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |