SCHEMBL7031311

SCHEMBL7031311

COc1nc(NC(=O)O)nc(OC)n1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
HTT P42858 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
CYP1A2 P05177 1/20 0.41
LMNA P02545 2/20 0.40
GAA P10253 2/20 0.40
POLB P06746 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
RECQL P46063 1/20 0.38
KMT2A Q03164 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8532151 0.90 GAA (0.49) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL8883302 0.83 MAPT (0.46) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL10908819 0.81 GAA (0.35) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL10499675 0.81 MAPT (0.45) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL11792363 0.78 MAPT (0.39) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL9480478 0.76 GAA (0.47) MAPTHTTNPSR1CYP1A2LMNA
SCHEMBL2473325 0.75 MAPT (0.37) MAPTCYP1A2LMNAPOLBALDH1A1
SCHEMBL3791688 0.75 CYP1A2 (0.72) MAPTHTTCYP1A2LMNAGAA
SCHEMBL4286264 0.75 GAA (0.46) MAPTHTTNPSR1CYP1A2GAA
SCHEMBL11792384 0.74 MAPT (0.39) MAPTHTTNPSR1CYP1A2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456120-B Bissulfonylamino substituted sulfonylurea compound, and preparation method and application thereof 郑州手性药物研究院有限公司 2024-06-18 CN disclosed
CN-114456120-A Bis-sulfonylamino substituted sulfonylurea compound and its preparation method and use 郑州手性药物研究院有限公司 2022-05-10 CN disclosed
EP-0562576-B1 Process for the preparation of phenyl (1,3,5-triazin-2-yl) carbamates KUREHA CHEMICAL IND CO LTD (JP) 2003-01-22 EP disclosed
EP-1209153-A2 Process for the preparation of phenyl (1,3,5-triazin-2-yl) carbamates KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-05-29 EP disclosed
US-5583231-A HERBICIDE ISHIHARA SANGYO KAISHA, LTD. (JP) 1996-12-10 US disclosed
US-5457084-A Herbicides use at low dosage ISHIHARA SANGYO KAISHA LTD. (JP) 1995-10-10 US disclosed
EP-0382437-B1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA CHEMICAL IND CO LTD (JP) 1995-08-16 EP disclosed
US-5380843-A Process for the preparation of phenyl (1,3,5-triazin-2-yl)carbamates KUREHA KAGAKU KOGYO K.K. (JP) 1995-01-10 US disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP disclosed
EP-0394059-A1 Herbicidal benzylsulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-10-24 EP disclosed
EP-0386001-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-12 EP disclosed
EP-0384602-A1 N-substituted-3-[(2,3-dimethylmaleimido) amino]-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-29 EP disclosed
EP-0382437-A1 N-substituted-3-(substituded hydrazino)-benzenesulfonamide derivatives, preparation process thereof and herbicidal compositions KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1990-08-16 EP disclosed
WO-1989000991-A1 HERBICIDAL SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-09 WO disclosed
EP-0301784-A1 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-02-01 EP disclosed
US-4746358-A PLANT GROWTH REGULATORS, HERBICIDES; N-TRIAZINYL-AMINOCARBONYL -1,4-BENZODIOXANESULFONAMIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-24 US disclosed
US-4659368-A HERBICIDES; PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1987-04-21 US disclosed
US-4502882-A HERBICIDES, PLANT GROWTH REGULATORS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1985-03-05 US disclosed
EP-0082681-A2 Herbicidal sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-06-29 EP disclosed