Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 15/20 | 0.73 |
| ▸ | MME | P08473 | 13/20 | 0.73 |
| ▸ | CPA1 | P15085 | 12/20 | 0.73 |
| ▸ | ACE2 | Q9BYF1 | 12/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7029386 | 0.87 | MME (0.68) | ACEMMECPA1ACE2 | |
| SCHEMBL7031211 | 0.87 | MME (0.68) | ACEMMECPA1ACE2 | |
| SCHEMBL7029391 | 0.87 | MME (0.68) | ACEMMECPA1ACE2 | |
| SCHEMBL7028022 | 0.86 | MME (0.74) | ACEMMECPA1ACE2 | |
| SCHEMBL7027395 | 0.86 | MME (0.74) | ACEMMECPA1ACE2 | |
| SCHEMBL7027401 | 0.86 | MME (0.74) | ACEMMECPA1ACE2 | |
| SCHEMBL7029885 | 0.86 | MME (0.67) | ACEMMECPA1ACE2 | |
| SCHEMBL7026712 | 0.86 | MME (0.67) | ACEMMECPA1ACE2 | |
| SCHEMBL7026704 | 0.86 | MME (0.67) | ACEMMECPA1ACE2 | |
| SCHEMBL7028034 | 0.84 | MME (0.72) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140984-B1 | SELECTIVE INHIBITORS OF MMP-12 | AVENTIS PHARMA INC (US) | 2003-02-12 | — | — | EP | claimed |