SCHEMBL70315

SCHEMBL70315

COC(=O)c1cccc2c1Oc1c(cccc1C(=O)OC)S2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.47
LMNA P02545 2/20 0.47
TRPA1 O75762 2/20 0.47
GAA P10253 2/20 0.47
TSHR P16473 1/20 0.46
ALDH1A1 P00352 2/20 0.44
CFTR P13569 1/20 0.44
HSD17B10 Q99714 1/20 0.44
POLB P06746 1/20 0.43
ATM Q13315 1/20 0.43
ALOX5 P09917 1/20 0.43
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA9 Q16790 2/20 0.40
CA5A P35218 1/20 0.40
ALOX15 P16050 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16724082 0.78 TRPA1 (0.47) KDM4ELMNATRPA1GAATSHR
SCHEMBL10556270 0.76 ALOX5 (0.57) KDM4ELMNATRPA1TSHRALDH1A1
SCHEMBL9511389 0.76 KDM4E (0.50) KDM4ELMNAGAATSHRALDH1A1
SCHEMBL9495694 0.73 ALOX5 (0.51) KDM4ELMNATRPA1GAATSHR
SCHEMBL1065556 0.70 PARP1 (0.66) KDM4ELMNATRPA1TSHRALDH1A1
SCHEMBL19717923 0.70 KDM4E (0.62) KDM4ELMNAGAATSHRALDH1A1
Dimethyl Phthalate SCHEMBL34630 0.70 TSHR (0.74) KDM4ELMNATSHRALDH1A1CFTR
Dimethyl Phthalate SCHEMBL29500970 0.70 TSHR (0.74) KDM4ELMNATSHRALDH1A1CFTR
Dimethyl Phthalate SCHEMBL790124 0.70 TSHR (0.74) KDM4ELMNATSHRALDH1A1CFTR
Dimethyl Phthalate SCHEMBL29669976 0.70 TSHR (0.74) KDM4ELMNATSHRALDH1A1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 KDM4E 717/4885LMNA 2207/4885TRPA1 150/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.