Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | HRH1 | P35367 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.57 |
| ▸ | CPT2 | P23786 | 2/20 | 0.53 |
| ▸ | CPT1A | P50416 | 2/20 | 0.53 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28029014 | 0.98 | MEN1 (0.65) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Glutarate SCHEMBL10496229 | 0.89 | MEN1 (0.56) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL4256715 | 0.87 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL17629809 | 0.87 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL1208087 | 0.87 | MEN1 (0.71) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL28171779 | 0.83 | MEN1 (0.67) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Aspartic Acid SCHEMBL10496248 | 0.83 | MEN1 (0.49) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL2994007 | 0.82 | MEN1 (0.65) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL28768760 | 0.81 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL25099750 | 0.81 | LMNA (0.63) | MEN1KMT2ACYP1A2HRH1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170182108-A1 | FERMENTED FOOD EXTRACT COMPOSITION | SHINSHU UNIVERSITY (JP) | 2017-06-29 | — | — | US | claimed |
| CN-106132407-A | Fermented food extracts compositions | 国立大学法人信州大学 | 2016-11-16 | — | — | CN | claimed |
| EP-3197445-B1 | PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA | SALAMA ZOSER B (DE) | 2021-04-28 | — | — | EP | disclosed |
| US-10328051-B2 | Proline or proline derivatives for the treatment of dementia | SALAMA ZOSER B (DE) | 2019-06-25 | — | — | US | disclosed |
| US-20170239215-A1 | PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA | SALAMA ZOSER B (DE) | 2017-08-24 | — | — | US | disclosed |
| EP-3197445-A1 | PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA | Salama, Zoser B. (DE) | 2017-08-02 | — | — | EP | disclosed |
| US-20170182108-A1 | FERMENTED FOOD EXTRACT COMPOSITION | SHINSHU UNIVERSITY (JP) | 2017-06-29 | — | — | US | disclosed |
| WO-2016200364-A1 | THERAPEUTIC COMPOSITIONS INCLUDING SkQ COMPOUNDS AND USES THEREOF | STEALTH PEPTIDES INTERNATIONAL, INC. (MC) | 2016-12-15 | — | — | WO | disclosed |
| CN-106132407-A | Fermented food extracts compositions | 国立大学法人信州大学 | 2016-11-16 | — | — | CN | disclosed |
| WO-2016046162-A1 | PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA | SALAMA ZOSER B (DE) | 2016-03-31 | — | — | WO | disclosed |
| EP-0770400-B1 | Acyl-L-carnitine labelled on the secondary acyl carbon atom and diagnostic agents containing it | JAPAN SCIENCE & TECH CORP (JP) | 2003-02-26 | — | — | EP | disclosed |
| US-5837219-A | Labelled acyl-L-carnitine and diagnostic agent | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 1998-11-17 | — | — | US | disclosed |
| EP-0770400-A2 | Labelled acyl-L-carnitine and diagnostic agent | Japan Science and Technology Corporation (JP) | 1997-05-02 | — | — | EP | disclosed |
| US-4883786-A | CARDIOTROPIC AGENTS | MAGIS FARMACEUTICI SRL (IT) | 1989-11-28 | — | — | US | disclosed |
| EP-0167115-B1 | NEW DERIVATIVES OF L-CARNITINE | MAGIS FARMACEUTICI S.P.A. (IT) | 1988-04-20 | — | — | EP | disclosed |
| US-4710468-A | FROM OPTICALLY ACTIVE SUBSTITUTED HYDROXYBUTYRIC ACID DERIVATIVES WITH OXIDOREDUCTASE | SIGMA-TAU INDUSTRIE PHARMACEUTICHE RIUNITE S.P.A. (IT) | 1987-12-01 | — | — | US | disclosed |
| EP-0167115-A2 | New derivatives of L-carnitine | MAGIS FARMACEUTICI S.P.A. (IT) | 1986-01-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10328051-B2 | Proline or proline derivatives for the treatment of dementia | PSEN2, PSEN1, PRNP | MEN1 4298/4885KMT2A 2678/4885CYP1A2 2826/4885 |
| US-20170182108-A1 | FERMENTED FOOD EXTRACT COMPOSITION | FIBP, PFKFB2, PFKFB1 | MEN1 2308/4885KMT2A 2292/4885CYP1A2 4090/4885 |
| US-20170239215-A1 | PROLINE OR PROLINE DERIVATIVES FOR THE TREATMENT OF DEMENTIA | PSEN2, PSEN1, PRNP | MEN1 4298/4885KMT2A 2678/4885CYP1A2 2826/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.