Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021186 | 0.88 | GPR84 (0.35) | GPR84FFAR4BACE1NAAA | |
| SCHEMBL7030009 | 0.86 | GPR84 (0.38) | GPR84GRM2MAOBCHKANAAA | |
| SCHEMBL8725458 | 0.85 | GPR84 (0.39) | GPR84MAOB | |
| SCHEMBL8725462 | 0.85 | GPR84 (0.39) | GPR84MAOB | |
| SCHEMBL7021194 | 0.85 | — | — | |
| SCHEMBL8387227 | 0.85 | — | — | |
| SCHEMBL7032286 | 0.84 | GPR84 (0.37) | GPR84MAOB | |
| SCHEMBL7026071 | 0.83 | RARB (0.39) | GPR84GRM2MAOB | |
| SCHEMBL8041175 | 0.82 | CYP17A1 (0.39) | GPR84MAOB | |
| SCHEMBL8518015 | 0.82 | CYP17A1 (0.39) | GPR84MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |