Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7021187 | 0.87 | KIF11 (0.36) | GPR84KIF11MAOB | |
| SCHEMBL7030011 | 0.84 | GPR84 (0.39) | GPR84KIF11MAOBNPC1 | |
| SCHEMBL7021197 | 0.84 | NPC1 (0.30) | NPC1 | |
| SCHEMBL7032285 | 0.84 | GPR84 (0.36) | GPR84MAOB | |
| SCHEMBL8518012 | 0.84 | CYP17A1 (0.39) | GPR84KIF11MAOBNPC1 | |
| SCHEMBL8041175 | 0.84 | CYP17A1 (0.39) | GPR84KIF11MAOBNPC1 | |
| SCHEMBL8518015 | 0.84 | CYP17A1 (0.39) | GPR84KIF11MAOBNPC1 | |
| SCHEMBL7026859 | 0.81 | ESR2 (0.33) | NPC1 | |
| SCHEMBL7026073 | 0.81 | RARB (0.43) | GPR84MAOBNPC1 | |
| SCHEMBL8518318 | 0.81 | GPR84 (0.36) | GPR84KIF11MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754668-B1 | Fluorobenzylether derivatives | ROLIC AG (CH) | 2003-02-05 | — | — | EP | disclosed |
| EP-0754668-A2 | Fluorobenzylether derivatives | Rolic AG (CH) | 1997-01-22 | — | — | EP | disclosed |