Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 6/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.38 |
| ▸ | ITGAV | P06756 | 4/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.38 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030532 | 0.93 | FPR2 (0.46) | ITGB1ITGA5FPR2TAOK1TAOK3 | |
| SCHEMBL7039077 | 0.93 | ITGB1 (0.41) | ITGB1ITGA5ITGB3ITGAVFPR2 | |
| SCHEMBL7036742 | 0.93 | ITGB1 (0.38) | ITGB1ITGA5ITGB3ITGAVFPR2 | |
| SCHEMBL7031208 | 0.93 | POLB (0.43) | ITGB1ITGA5ITGB3ITGAVFPR2 | |
| SCHEMBL7032315 | 0.92 | PLAU (0.38) | ITGB1ITGA5ITGB3ITGAVFPR2 | |
| SCHEMBL7030525 | 0.91 | FPR2 (0.44) | ITGB1ITGA5FPR2MEN1KMT2A | |
| SCHEMBL7034485 | 0.91 | FPR2 (0.48) | ITGB1ITGA5FPR2MEN1KMT2A | |
| SCHEMBL7034088 | 0.90 | NPC1 (0.42) | MEN1KMT2A | |
| SCHEMBL7032372 | 0.89 | ITGB1 (0.41) | ITGB1ITGA5ITGB3ITGAVPOLB | |
| SCHEMBL7032164 | 0.89 | ITGB1 (0.44) | ITGB1ITGA5ITGB3ITGAVMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030186967-A1 | Acylresorcinol derivatives are selective vitronectin receptor inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 2003-10-02 | — | — | US | claimed |
| US-20030186967-A1 | Acylresorcinol derivatives are selective vitronectin receptor inhibitors | AMERICAN HOME PRODUCTS CORPORATION (US) | 2003-10-02 | — | — | US | disclosed |
| WO-1999052879-A1 | ACYLRESORCINOL DERIVATIVES AS SELECTIVE VITRONECTIN RECEPTOR INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186967-A1 | Acylresorcinol derivatives are selective vitronectin receptor inhibitors | ASGR1, TEK, APLNR | ITGB1 306/4885ITGA5 450/4885ITGB3 403/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.