Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 3/20 | 0.50 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.44 |
| ▸ | HTR3B | O95264 | 3/20 | 0.44 |
| ▸ | HTR3A | P46098 | 3/20 | 0.44 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.44 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7023134 | 0.88 | PDE3A (0.62) | PDE3ACA12CA9ARPARP1 | |
| SCHEMBL3768245 | 0.86 | PDE3A (0.64) | PDE3ACA12CA9ARPARP1 | |
| SCHEMBL16262805 | 0.84 | ADRB1 (0.50) | PDE3AADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL7026070 | 0.84 | KIF11 (0.55) | PDE3AKDRPARP1KDM4EMAPT | |
| SCHEMBL7029687 | 0.84 | PDE3A (0.55) | PDE3AHTTHSD17B10KDM4EPDE3B | |
| Hydrochloric Acid SCHEMBL22160862 | 0.83 | ADRB1 (0.49) | PDE3AADRB1HTR3EHTR3BHTR3A | |
| SCHEMBL31296617 | 0.80 | PDE3A (0.46) | PDE3ACA12CA9HTR1AHTR2A | |
| SCHEMBL7024817 | 0.80 | PDE3A (0.46) | PDE3ACA12CA9HTR1AHTR2A | |
| SCHEMBL26133119 | 0.80 | PDE3A (0.46) | PDE3ACA12CA9HTR1AHTR2A | |
| SCHEMBL7029333 | 0.76 | DRD4 (0.55) | HTTHSD17B10KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775697-B1 | Process for producing 1-substituted tetrahydroquinazolindionen | SUMITOMO CHEMICAL CO (JP) | 2003-02-12 | — | — | EP | disclosed |
| EP-0775697-A1 | Process for producing 1-substituted tetrahydroquinazolindionen | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-05-28 | — | — | EP | disclosed |