Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25B | P30305 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18289621 | 0.75 | HPGD (0.83) | L3MBTL1ALOX12HPGDCXCR2ALDH1A1 | |
| SCHEMBL4957626 | 0.75 | HPGD (0.83) | L3MBTL1ALOX12HPGDCXCR2ALDH1A1 | |
| SCHEMBL18289622 | 0.75 | HPGD (0.83) | L3MBTL1ALOX12HPGDCXCR2ALDH1A1 | |
| SCHEMBL395942 | 0.75 | HPGD (0.83) | L3MBTL1ALOX12HPGDCXCR2ALDH1A1 | |
| SCHEMBL11805322 | 0.75 | DNM1 (0.71) | L3MBTL1HPGDALDH1A1RECQLMEN1 | |
| SCHEMBL9560460 | 0.75 | IDO1 (0.49) | ALOX12HPGDALDH1A1RECQLMEN1 | |
| SCHEMBL2037194 | 0.74 | MAPT (0.52) | L3MBTL1ALOX12HPGDALDH1A1HSD17B10 | |
| SCHEMBL27491991 | 0.73 | KMT2A (0.57) | L3MBTL1ALDH1A1MEN1KMT2ACA1 | |
| Benzoquinone SCHEMBL28539805 | 0.73 | ALDH1A1 (0.56) | ALDH1A1RECQLHSD17B10CA1CA2 | |
| SCHEMBL29098353 | 0.71 | DNM1 (0.46) | L3MBTL1ALDH1A1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100478-A9 | ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES | CAVALIER DISCOVERY (US) | 2003-03-27 | — | — | WO | disclosed |
| WO-2002100478-A2 | ACCELERATORS FOR INCREASING THE RATE OF FORMATION OF FREE RADICALS AND REACTIVE OXYGEN SPECIES | CAVALIER DISCOVERY (US) | 2002-12-19 | — | — | WO | disclosed |