⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7031349 | 0.79 | — | — | |
| SCHEMBL7367993 | 0.78 | — | — | |
| SCHEMBL7031350 | 0.77 | — | — | |
| SCHEMBL12337440 | 0.64 | — | — | |
| SCHEMBL28025732 | 0.63 | — | — | |
| SCHEMBL7027948 | 0.60 | GABRA1 (0.34) | — | |
| SCHEMBL127337 | 0.60 | — | — | |
| SCHEMBL10049019 | 0.60 | — | — | |
| SCHEMBL13788685 | 0.60 | — | — | |
| SCHEMBL8912315 | 0.59 | TACR1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183202-B2 | — | — | 2012-05-22 | — | — | US | disclosed |
| US-20090203583-A1 | Use of Type-B Lantibiotic-Based Compounds having Antimicrobial Activity | NOVACTA BIOSYSTEMS LIMITED (GB) | 2009-08-13 | — | — | US | disclosed |