SCHEMBL70329

SCHEMBL70329

[c]1cc2cc3ccccc3cc2c2ccccc12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.43
HSD17B10 Q99714 5/20 0.43
HIF1A Q16665 2/20 0.43
CYP1B1 Q16678 1/20 0.43
HTR2A P28223 1/20 0.38
ESR1 P03372 2/20 0.35
ESR2 Q92731 2/20 0.35
HPGD P15428 3/20 0.34
GLA P06280 2/20 0.34
ACHE P22303 2/20 0.34
MAPT P10636 1/20 0.34
CYP1A2 P05177 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
CYP2A6 P11509 1/20 0.33
TSHR P16473 1/20 0.33
NQO1 P15559 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NQO2 P16083 1/20 0.33
KDM4E B2RXH2 2/20 0.32
GAA P10253 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8733623 0.98 ALDH1A1 (0.41) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL2452867 0.88 ALDH1A1 (0.61) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL1067479 0.86 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27494442 0.85 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL25131 0.82 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27616289 0.80 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL9958428 0.77 ESR1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1ESR1
SCHEMBL1168013 0.77 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1ESR1
SCHEMBL1168422 0.76 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27339348 0.75 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3810 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344375-A Dicarbazole compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2024-07-16 CN claimed
CN-118324788-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-07-12 CN claimed
EP-4398362-A1 POLYMER SOLID ELECTROLYTE AND APPLICATION Nanjing Bochi New Energy Co., Ltd. (CN) 2024-07-10 EP claimed
CN-114853702-B Naphtho heteroaromatic compound, organic electroluminescent device and display device 阜阳欣奕华材料科技有限公司 2024-07-02 CN claimed
CN-118239966-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-06-25 CN claimed
CN-118076128-A Light emitting device, manufacturing method thereof and display panel 北京维信诺科技有限公司 2024-05-24 CN claimed
CN-118063494-A Organic electroluminescent compound with core structure of boron-containing polycyclic aza-aromatic hydrocarbon and application thereof 吉林省元合电子材料有限公司 2024-05-24 CN claimed
WO-2024099269-A1 ARYLAMIDE COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, USE THEREOF 华东师范大学 2024-05-16 WO claimed
CN-118027085-A Organic electroluminescent compound and application thereof 宁波卢米蓝新材料有限公司 2024-05-14 CN claimed
CN-118026880-A Aryl amide compound, pharmaceutical composition containing same and application thereof 华东师范大学 2024-05-14 CN claimed
EP-1000070-A1 SILICON-CONTAINING CHAIN EXTENDERS CARDIAC CRC NOMINEES PTY. LTD. (AU) 2000-05-17 EP claimed
EP-0984997-A4 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY LTD (AU) 2000-03-29 EP claimed
EP-0984997-A1 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY. LTD. (AU) 2000-03-15 EP claimed
WO-1999003863-A1 SILICON-CONTAINING CHAIN EXTENDERS CARDIAC CRC NOMINEES PTY. LTD. (AU) 1999-01-28 WO claimed
WO-1998054242-A1 SILICON-BASED POLYCARBONATES CARDIAC CRC NOMINEES PTY. LTD. (AU) 1998-12-03 WO claimed
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP claimed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US claimed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP claimed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US claimed