SCHEMBL8733623

SCHEMBL8733623

[c]1cc2cc3cc4ccccc4cc3cc2c2ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.41
HSD17B10 Q99714 5/20 0.41
HIF1A Q16665 2/20 0.41
CYP1B1 Q16678 1/20 0.41
HTR2A P28223 1/20 0.36
TDP1 Q9NUW8 2/20 0.34
CYP3A4 P08684 2/20 0.34
ALOX15 P16050 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
HBB P68871 1/20 0.34
ESR1 P03372 2/20 0.34
ESR2 Q92731 2/20 0.34
HPGD P15428 3/20 0.33
GLA P06280 2/20 0.33
ACHE P22303 2/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 3/20 0.32
NQO1 P15559 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL70329 0.98 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL2452867 0.86 ALDH1A1 (0.61) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL1067479 0.85 ALDH1A1 (0.54) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27494442 0.83 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL25131 0.81 ALDH1A1 (0.46) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27616289 0.79 ALDH1A1 (0.43) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL9958428 0.76 ESR1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1ESR1
SCHEMBL1168013 0.75 ALDH1A1 (0.44) ALDH1A1HSD17B10HIF1ACYP1B1TDP1
SCHEMBL1168422 0.74 ALDH1A1 (0.50) ALDH1A1HSD17B10HIF1ACYP1B1HTR2A
SCHEMBL27339348 0.73 ALDH1A1 (0.39) ALDH1A1HSD17B10HIF1ACYP1B1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP claimed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US claimed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US claimed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP claimed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US claimed
EP-0697387-B1 Improved method for the preparation of iodonium salts DOW CORNING (US) 1998-04-22 EP disclosed
US-5624762-A Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1997-04-29 US disclosed
US-5594042-A RELEASE AGENTS FOR PRESSURE SENSITIVE ADHESIVES DOW CORNING CORPORATION (US) 1997-01-14 US disclosed
EP-0697449-A2 Radiation curable compositions containing vinyl ether functional polyorganosiloxanes DOW CORNING CORPORATION (US) 1996-02-21 EP disclosed
EP-0697387-A2 Improved method for the preparation of iodonium salts DOW CORNING CORPORATION (US) 1996-02-21 EP disclosed
US-5426222-A Mixing iodoarene dicarboxylate, solvent, adding acid to form homogeneous reaction mixture, reacting with benzene or substituted benzene, stripping solvent DOW CORNING CORPORATION (US) 1995-06-20 US disclosed