Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3154189 | 0.83 | MEN1 (0.31) | ALDH1A1MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL5838371 | 0.83 | HTR2C (0.33) | HTR2CHTR2AHTR2B | |
| SCHEMBL1452679 | 0.82 | TP53 (0.34) | SLC6A2SLC6A4SLC6A3HTR2CHTR2A | |
| SCHEMBL1451568 | 0.81 | PBRM1 (0.32) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL1452430 | 0.81 | — | — | |
| SCHEMBL1451959 | 0.81 | PBRM1 (0.35) | ALDH1A1MEN1KMT2AHTR2CHTR2A | |
| SCHEMBL7593800 | 0.79 | MEN1 (0.34) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7027942 | 0.79 | GABRA1 (0.36) | MEN1KMT2A | |
| SCHEMBL7031598 | 0.78 | GABRA1 (0.36) | SLC6A2HTR2CHTR2BCYP1A2CA1 | |
| SCHEMBL4623138 | 0.77 | PDCD1 (0.39) | ALDH1A1HTR2AHTR2BCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104370681-A | Synthesis method of vinyl-bridged dialkylindene compound | SHANGHAI ADVANCED RES INST CAS | 2015-02-25 | — | — | CN | disclosed |
| EP-0889059-B1 | Catalyst based on monoazadiene metal complexes | BAYER AG (DE) | 2003-02-12 | — | — | EP | disclosed |
| US-20020052446-A1 | Composition based on monofluorometal complexes | BAYER AKTIENGESELLSCHAFT (DE) | 2002-05-02 | — | — | US | disclosed |
| US-5965678-A | Catalyst system based on monoazadiene metal complexes | BAYER AG (DE) | 1999-10-12 | — | — | US | disclosed |
| EP-0889059-A1 | Catalyst based on monoazadiene metal complexes | BAYER AG (DE) | 1999-01-07 | — | — | EP | disclosed |