Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 6/20 | 0.52 |
| ▸ | ACE | P12821 | 5/20 | 0.52 |
| ▸ | CPA1 | P15085 | 5/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7165248 | 1.00 | MME (0.58) | MMEACE2ACECPA1NAALAD2 | |
| SCHEMBL2880995 | 1.00 | MME (0.58) | MMEACE2ACECPA1NAALAD2 | |
| SCHEMBL9657150 | 1.00 | MME (0.58) | MMEACE2ACECPA1NAALAD2 | |
| SCHEMBL15739447 | 0.91 | MME (0.62) | MMEACE2ACECPA1 | |
| SCHEMBL10359803 | 0.89 | MME (0.55) | MMEACE2ACECPA1MMP2 | |
| SCHEMBL19932059 | 0.89 | FCER2 (0.51) | MMEACE | |
| SCHEMBL7030032 | 0.87 | ALDH1A1 (0.60) | — | |
| SCHEMBL10907014 | 0.87 | ALDH1A1 (0.60) | — | |
| SCHEMBL6545851 | 0.87 | ALDH1A1 (0.60) | — | |
| SCHEMBL9169974 | 0.87 | ALDH1A1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103626840-A | Preparation method for aspartame from raw materials containing chiral isomer | CHANGZHOU GUANGHUI BIOTECHNOLOGY CO LTD | 2014-03-12 | — | — | CN | claimed |
| EP-0986575-B1 | METHOD FOR PREPARING SALTS OF ASPARTAME FROM N-PROTECTED ASPARTAME | HOLLAND SWEETENER CO (NL) | 2003-04-23 | — | — | EP | claimed |
| EP-0294860-B1 | PROCESS FOR THE PREPARATION OF ASPARTYLPHENYLALANINE METHYL ESTER FROM N-FORMYLASPARTYLPHENYLALANINE METHYL ESTER | DSM N.V. (NL) | 1992-12-16 | — | — | EP | claimed |
| EP-0186378-B1 | PROCESS FOR THE PREPARATION OF N-FORMYL-ALPHA-ASPARTYL PHENYLALANINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-01-15 | — | — | EP | claimed |
| CN-103626840-A | Preparation method for aspartame from raw materials containing chiral isomer | CHANGZHOU GUANGHUI BIOTECHNOLOGY CO LTD | 2014-03-12 | — | — | CN | disclosed |
| CN-102206246-A | Aqueous synthesis method for N-formyl-alpha-L-aspartoyl-L-phenylalanine | JIANG WU | 2011-10-05 | — | — | CN | disclosed |
| CN-102206246-A | Aqueous synthesis method for N-formyl-alpha-L-aspartoyl-L-phenylalanine | JIANG WU | 2011-10-05 | — | — | CN | disclosed |
| WO-2002085840-A9 | PROCESS FOR PRODUCING N-FORMYLAMINO ACID AND UTILIZATION THEREOF | AJINOMOTO KK (JP) | 2003-03-06 | — | — | WO | disclosed |
| WO-2002085840-A1 | PROCESS FOR PRODUCING N-FORMYLAMINO ACID AND UTILIZATION THEREOF | AJINOMOTO CO., INC. (JP) | 2002-10-31 | — | — | WO | disclosed |
| EP-0186378-B1 | PROCESS FOR THE PREPARATION OF N-FORMYL-ALPHA-ASPARTYL PHENYLALANINE | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-01-15 | — | — | EP | disclosed |
| EP-0127411-B1 | METHOD OF PREPARING ALPHA-L-ASPARTYL-L-PHENYLALANINE METHYL ESTER AND ITS HYDROCHLORIDE | AJINOMOTO CO., INC. (JP) | 1988-08-10 | — | — | EP | disclosed |
| US-4606854-A | Method of preparing α-L-aspartyl-L-phenylalanine methyl ester and its hydrochloride | AJINOMOTO CO., INC. (JP) | 1986-08-19 | — | — | US | disclosed |
| EP-0186378-A2 | Process for the preparation of N-formyl-alpha-aspartyl phenylalanine | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1986-07-02 | — | — | EP | disclosed |
| EP-0127411-A2 | Method of preparing alpha-l-aspartyl-l-phenylalanine methyl ester and its hydrochloride | AJINOMOTO CO., INC. (JP) | 1984-12-05 | — | — | EP | disclosed |