SCHEMBL703295

SCHEMBL703295

COC(=O)CS(=O)(=O)Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10622350 0.78 TSHR (0.52)
SCHEMBL1968530 0.76
SCHEMBL1123070 0.76
SCHEMBL977691 0.75 GAA (0.50)
SCHEMBL770916 0.75 TSHR (0.55)
SCHEMBL5328813 0.74 TSHR (0.46)
SCHEMBL13457619 0.74
SCHEMBL8375840 0.74 TSHR (0.46)
SCHEMBL15800899 0.74 TSHR (0.46)
SCHEMBL10260586 0.74 TSHR (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 604 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104003913-B The preparation method of E-3,4-dihydroxyphenyl vinylic sulfonamides and sulfonates compounds and the application as neuroprotective thereof PEKING UNIVERSITY (CN) 2015-10-07 CN claimed
US-20260109711-A1 MACROCYCLIC SULFONAMIDE MODULATORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2026-04-23 US disclosed
US-20260098029-A1 KIF18A INHIBITORS AMGEN INC. (US) 2026-04-09 US disclosed
US-20260062430-A1 INHIBITORS OF KIF18A AND USES THEREOF ACCENT THERAPEUTICS INC (US) 2026-03-05 US disclosed
EP-4146651-B1 SULFONYLAMIDINE SUBSTITUTED COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS NINGXIA ACADEMY AGRICULTURE & FORESTRY SCIENCES (CN) 2026-03-04 EP disclosed
US-20260049080-A1 WILD TYPE KIT INHIBITORS BLUEPRINT MEDICINES CORP (US) 2026-02-19 US disclosed
EP-4688742-A1 CYCLOHEXYL OR HETEROCYCLOALKYL BETA-HYDROXY ALKYL AMINES FOR USE IN THE TREATMENT OF HYPERGLYCAEMIA AND DISORDERS CHARACTERISED BY HYPERGLYCAEMIA Atrogi AB (SE) 2026-02-11 EP disclosed
US-12509442-B2 KIF18A inhibitors AMGEN INC. (US) 2025-12-30 US disclosed
US-12466821-B2 Antiviral pyridopyrazinedione compounds NOVARTIS AG (CH) 2025-11-11 US disclosed
US-12459932-B2 KIF18A inhibitors AMGEN INC. (US) 2025-11-04 US disclosed
EP-0107979-B1 NOVEL PHENYL-SUBSTITUTED SULFONAMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1988-10-12 EP disclosed
US-4772703-A LIPOXYGENASE INHIBITORS AMERICAN HOME PRODUCTS CORPORATION (US) 1988-09-20 US disclosed
US-4741761-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-05-03 US disclosed
US-4620870-A HERBICIDES E. I. DU PONT DE NEMOURS AND COMPANY (US) 1986-11-04 US disclosed
US-4586950-A HERBICIDES E. I. DU PONT DE NEMOURS & COMPANY (US) 1986-05-06 US disclosed
EP-0107979-A1 Novel phenyl-substituted sulfonamides E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-09 EP disclosed
US-4283416-A Fungicidal, miticidal and ovicidal alkoxycarbonylalkyl-substituted and carbamylalkyl-substituted N-haloalkylthiosulfonamides CHEVRON RESEARCH COMPANY (US) 1981-08-11 US disclosed
US-4230875-A Fungicidal, miticidal and ovicidal alkoxycarbonylalkyl-substituted and carbamylalkyl-substituted N-haloalkylthiosulfonamides CHEVRON RESEARCH COMPANY (US) 1980-10-28 US disclosed
US-4112237-A Fungicidal, miticidal and ovicidal alkoxycarbonylalkyl-substituted and carbamylalkyl-substituted N-haloalkylthiosulfonamides CHEVRON RESEARCH COMPANY (US) 1978-09-05 US disclosed
US-4008267-A ANALYZING AB KABI (SW) 1977-02-15 US disclosed