Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7032987

N.N.O=C(O)CC(C(O)=S)c1nc2ccccc2s1

nearest known ligand 0.51

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
KMT2A Q03164 2/20 0.50
HPGD P15428 6/20 0.49
CYP1A2 P05177 2/20 0.49
CYP2C19 P33261 2/20 0.49
HSD17B10 Q99714 2/20 0.49
CYP2C9 P11712 1/20 0.49
HIF1A Q16665 1/20 0.49
ALOX15 P16050 1/20 0.48
HTT P42858 1/20 0.48
ALOX5 P09917 1/20 0.45
LOXL2 Q9Y4K0 1/20 0.44
CSNK1D P48730 1/20 0.44
NCS1 P62166 1/20 0.44
RAB9A P51151 3/20 0.44
ALDH1A1 P00352 2/20 0.44
POLB P06746 2/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL402777 0.99 PKM (0.52) PKMSMN1; SMN2KMT2AHPGDCYP1A2
SCHEMBL30944811 0.99 PKM (0.52) PKMSMN1; SMN2KMT2AHPGDCYP1A2
Methylamine SCHEMBL10867358 0.95 PKM (0.52) PKMSMN1; SMN2KMT2AHPGDCYP1A2
Dimethylamine SCHEMBL10597492 0.93 PKM (0.51) PKMSMN1; SMN2KMT2AHPGDCYP1A2
Diethylamine SCHEMBL10597110 0.90 PKM (0.48) PKMSMN1; SMN2KMT2AHPGDCYP1A2
SCHEMBL9443162 0.90 LOXL2 (0.54) PKMSMN1; SMN2KMT2AHPGDCYP1A2
Ammonia Solution, Strong SCHEMBL7032984 0.89 HPGD (0.51) PKMSMN1; SMN2KMT2AHPGDCYP1A2
SCHEMBL402776 0.87 HPGD (0.53) PKMSMN1; SMN2KMT2AHPGDCYP1A2
SCHEMBL2856934 0.87 HPGD (0.56) PKMSMN1; SMN2KMT2AHPGDCYP1A2
SCHEMBL9443228 0.87 PKM (0.46) PKMSMN1; SMN2KMT2AHPGDCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0996769-B1 COMPOSTION FOR TEMPORARILY PROTECTING METAL PARTS AGAINST CORROSION, PREPARATION AND APPLICATION METHODS AND METAL PARTS OBTAINED FROM SAID COMPOSTION LORRAINE LAMINAGE (FR) 2003-03-05 EP claimed
EP-0183647-B1 ANTI-CORROSIVE AQUEOUS PAINTS CIBA-GEIGY AG (CH) 1989-02-15 EP disclosed
US-4612049-A BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID CIBA-GEIGY CORPORATION (US) 1986-09-16 US disclosed
EP-0183647-A1 Anti-corrosive aqueous paints CIBA-GEIGY AG (CH) 1986-06-04 EP disclosed
EP-0128862-A2 Anti-corrosive coating composition CIBA-GEIGY AG (CH) 1984-12-19 EP disclosed