Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 9/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | UQCRB | P14927 | 1/20 | 0.44 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | LOX | P28300 | 1/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9325260 | 0.83 | CA2 (0.78) | CA2ALDH1A1LMNALOXCYP3A4 | |
| SCHEMBL18531400 | 0.82 | ALDH1A1 (0.54) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL9813465 | 0.82 | ALDH1A1 (0.48) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL12062117 | 0.81 | CA2 (0.56) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL7033893 | 0.81 | ALDH1A1 (0.53) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL18503868 | 0.80 | HTT (0.61) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL3256579 | 0.79 | ALDH1A1 (0.59) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL9906397 | 0.79 | ALDH1A1 (0.59) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL11779353 | 0.79 | ALDH1A1 (0.48) | CA2ALDH1A1CA1NPC1RAB9A | |
| SCHEMBL13483410 | 0.79 | HDAC8 (0.45) | CA2ALDH1A1CA1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0841323-B1 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL CO (JP) | 2003-03-05 | — | — | EP | disclosed |
| US-6201131-B1 | REACTING A 2-(ARYLSUFONYL) ETHANOL DERIVATIVE WITH AN ACID ANHYDRIDE IN PRESENCE OF A BASE, FURTHER REACTING THIS WITH AN AROMATIC HALIDE IN THE PRESENCE OF A PALLADIUM CATALYST; USEFUL AS INTERMEDIATES TO DRUGS, AGROCHEMICALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2001-03-13 | — | — | US | disclosed |
| US-5902905-A | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1999-05-11 | — | — | US | disclosed |
| EP-0841323-A2 | Method for producing arylvinylsulfone | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1998-05-13 | — | — | EP | disclosed |