SCHEMBL7033091

SCHEMBL7033091

C=CS(=O)(=O)c1cccc(N(C)C)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.49
CA2 P00918 2/20 0.49
CA9 Q16790 2/20 0.49
CA1 P00915 1/20 0.49
CA4 P22748 1/20 0.49
ALDH1A1 P00352 3/20 0.41
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.39
MAPT P10636 2/20 0.39
NPC1 O15118 1/20 0.39
TP53 P04637 1/20 0.39
XBP1 P17861 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
MDM2 Q00987 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
HSD17B10 Q99714 1/20 0.39
FEN1 P39748 1/20 0.39
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749784 0.83 CA12 (0.38) CA12CA2CA9CA1CA4
SCHEMBL7029934 0.81 ALDH1A1 (0.46) ALDH1A1TSHRLMNAMAPTNPC1
SCHEMBL54845 0.80 TSHR (0.50) CA12CA2CA9CA1CA4
SCHEMBL23945028 0.80 CA12 (0.43) CA12CA2CA9CA1CA4
SCHEMBL10348034 0.79 NSD2 (0.54) CA12CA2CA9CA1CA4
SCHEMBL4946122 0.79 CA12 (0.56) CA12CA2CA9CA1CA4
SCHEMBL5499811 0.78 NSD2 (0.53) CA12CA2CA9CA1CA4
Hydrochloric Acid SCHEMBL27809968 0.78 NSD2 (0.53) CA12CA2CA9CA1CA4
SCHEMBL11698555 0.77 CA12 (0.54) CA12CA2CA9CA1CA4
SCHEMBL7896101 0.76 EGFR (0.48) CA12CA2CA9CA1CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2855597-B1 REACTIVE DYES, THEIR PREPARATION AND THEIR USE HUNTSMAN ADVANCED MAT (SWITZERLAND) GMBH (CH) 2017-06-07 EP disclosed
EP-0841323-B1 Method for producing arylvinylsulfone SUMITOMO CHEMICAL CO (JP) 2003-03-05 EP disclosed
US-6399833-B1 CRYSTALLIZATION; DISSOLVING IN SOLVENT SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-06-04 US disclosed
EP-1055666-A1 PROCESS FOR PRODUCING ARYL VINYL SULFONE SOLUTION AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-11-29 EP disclosed
US-5902905-A Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-11 US disclosed
EP-0841323-A2 Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-13 EP disclosed