SCHEMBL7029934

SCHEMBL7029934

C=CS(=O)(=O)c1cccc(N(CC)CC)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
CYP3A4 P08684 1/20 0.46
CNR2 P34972 8/20 0.39
CNR1 P21554 6/20 0.39
TSHR P16473 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD11B1 P28845 1/20 0.38
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
ALDH3A1 P30838 1/20 0.37
ALDH1A3 P47895 1/20 0.37
MEN1 O00255 1/20 0.37
RORC P51449 1/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 2/20 0.36
NPC1 O15118 1/20 0.36
TP53 P04637 1/20 0.36
XBP1 P17861 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749784 0.86 CA12 (0.38) ALDH1A1TSHRSMN1; SMN2MAPTRORC
SCHEMBL6854169 0.81 ALDH1A1 (0.55) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL7033091 0.81 CA12 (0.49) ALDH1A1TSHRSMN1; SMN2MAPTMAPK1
SCHEMBL30302484 0.81 ALDH1A1 (0.55) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL8773481 0.80 ALDH1A1 (0.53) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL5945169 0.80 ALDH1A1 (0.52) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL6571778 0.77 ALDH1A1 (0.49) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL11526370 0.77 RAB9A (0.53) ALDH1A1CYP3A4CNR2CNR1TSHR
SCHEMBL54845 0.76 TSHR (0.50) ALDH1A1TSHRSMN1; SMN2MAPTMAPK1
SCHEMBL11523408 0.75 ALDH1A1 (0.47) ALDH1A1CYP3A4CNR2CNR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0841323-B1 Method for producing arylvinylsulfone SUMITOMO CHEMICAL CO (JP) 2003-03-05 EP disclosed
EP-1055666-A1 PROCESS FOR PRODUCING ARYL VINYL SULFONE SOLUTION AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2000-11-29 EP disclosed
US-5902905-A Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-05-11 US disclosed
EP-0841323-A2 Method for producing arylvinylsulfone SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-05-13 EP disclosed