Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA3 | P07451 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.41 |
| ▸ | GABRE | P78334 | 1/20 | 0.41 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4385059 | 0.82 | APP (0.45) | APPCA12CA2CA3CA9 | |
| SCHEMBL7031654 | 0.79 | FFAR1 (0.50) | APPESR1ESR2LMNACYP3A4 | |
| SCHEMBL11214760 | 0.78 | APP (0.50) | APPCA12CA2CA3CA9 | |
| SCHEMBL17578918 | 0.78 | KCNH2 (0.55) | CA12CA2CA9GABRPGABRD | |
| SCHEMBL14575100 | 0.76 | GABRP (0.41) | APPCA2CA9GABRPGABRD | |
| SCHEMBL10453412 | 0.76 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL16380473 | 0.76 | KCNH2 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12523558 | 0.76 | CYP2C19 (0.60) | APPCA12CA2CA3CA9 | |
| SCHEMBL10453407 | 0.76 | GABRP (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2229991 | 0.76 | GABRP (0.41) | CA12CA2CA9CA14GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109734686-B | Catalytic synthesis method of 2-substituted benzofuran compound | 浙江万里学院 | 2022-07-01 | — | — | CN | claimed |
| CN-110078622-B | Synthetic method of 4-ethoxy-1, 1,2,4,5, 6-hexahydro cyclobutane naphthaline-2-benzoate | 安阳工学院 | 2022-02-08 | — | — | CN | claimed |
| CN-109734686-B | Catalytic synthesis method of 2-substituted benzofuran compound | 浙江万里学院 | 2022-07-01 | — | — | CN | disclosed |
| CN-110078622-B | Synthetic method of 4-ethoxy-1, 1,2,4,5, 6-hexahydro cyclobutane naphthaline-2-benzoate | 安阳工学院 | 2022-02-08 | — | — | CN | disclosed |
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2003-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065117-A1 | Modified silicone compound, process of producing the same, and cured object obtained therefrom | ORMDL3, SGMS1, HEATR1 | APP 3734/4885CA12 2045/4885CA2 1494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.