Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.35 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045556 | 0.71 | SMN1; SMN2 (0.47) | SLC6A3SLC6A2SLC6A4CFTRGOPC | |
| SCHEMBL30434450 | 0.71 | SMN1; SMN2 (0.46) | SLC6A3KCNH2SLC6A2SLC6A4CFTR | |
| SCHEMBL27626896 | 0.71 | CFTR (0.44) | SLC6A3KCNH2SLC6A2SLC6A4CFTR | |
| SCHEMBL27725257 | 0.70 | CYP1A2 (0.37) | ADRB2ADRB1ADRB3KDM4CCFTR | |
| SCHEMBL16297957 | 0.70 | SLC6A3 (0.41) | SLC6A3SLC6A2SLC6A4SMN1; SMN2LMNA | |
| SCHEMBL27787771 | 0.69 | SLC6A2 (0.52) | SLC6A3KCNH2SLC6A2SLC6A4CFTR | |
| SCHEMBL27501037 | 0.69 | ADRB2 (0.38) | ADRB2ADRB1ADRB3SLC6A3KCNH2 | |
| SCHEMBL27921940 | 0.68 | ADRB2 (0.39) | ADRB2ADRB1ADRB3SLC6A3KCNH2 | |
| SCHEMBL9682763 | 0.67 | NAPRT (0.42) | ADRB2ADRB1ADRB3SLC6A3SLC6A2 | |
| SCHEMBL28900068 | 0.67 | CYP2A6 (0.44) | SLC6A3SLC6A2SLC6A4CFTRGOPC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0676409-B1 | Erythromycin derivatives, their process for preparation and their application as medicaments | AVENTIS PHARMA SA (FR) | 2003-03-19 | — | — | EP | claimed |
| EP-0676409-B1 | Erythromycin derivatives, their process for preparation and their application as medicaments | AVENTIS PHARMA SA (FR) | 2003-03-19 | — | — | EP | disclosed |
| CN-1059445-C | Novel derivatives of erythromycin, their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-12-13 | — | — | CN | disclosed |
| CN-1126997-A | Novel erythromycin derivatives, method for preparing same and use thereof as drugs | ROUSSEL UCLAF (FR) | 1996-07-17 | — | — | CN | disclosed |
| EP-0676409-A1 | Erythromycin derivatives, their process for preparation and their application as medicaments | ROUSSEL UCLAF (FR) | 1995-10-11 | — | — | EP | disclosed |