Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.54 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | CMA1 | P23946 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.40 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GNRHR | P30968 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7036120 | 0.91 | PTGDR2 (0.55) | PTGDR2CTSGCMA1ARSMN1; SMN2 | |
| SCHEMBL7035111 | 0.88 | PTGDR2 (0.69) | PTGDR2CTSGCMA1ARSMN1; SMN2 | |
| SCHEMBL7028807 | 0.87 | SLC12A2 (0.51) | PTGDR2CTSGCMA1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7034397 | 0.85 | PTGDR2 (0.53) | PTGDR2CTSGCMA1ARSMN1; SMN2 | |
| SCHEMBL4452536 | 0.80 | CMA1 (0.56) | PTGDR2CTSGCMA1SMN1; SMN2MAPT | |
| SCHEMBL7030671 | 0.79 | PTGDR2 (0.67) | PTGDR2CTSGCMA1ARALDH1A1 | |
| SCHEMBL4450800 | 0.77 | CTSG (0.49) | PTGDR2CTSGCMA1ARKMT2A | |
| SCHEMBL14577952 | 0.76 | PTGDR2 (0.67) | PTGDR2CTSGCMA1ARSMN1; SMN2 | |
| SCHEMBL4452004 | 0.75 | CMA1 (0.51) | PTGDR2CTSGCMA1ALDH1A1MAPT | |
| SCHEMBL4307028 | 0.74 | SLC12A2 (0.67) | PTGDR2CTSGCMA1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | TEIJIN LIMITED (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | CMA1, CTRL, CPA4 | PTGDR2 2898/4885CTSG 204/4885CMA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.