Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.67 |
| ▸ | CTSG | P08311 | 1/20 | 0.60 |
| ▸ | CMA1 | P23946 | 1/20 | 0.60 |
| ▸ | AR | P10275 | 3/20 | 0.49 |
| ▸ | PDPK1 | O15530 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035111 | 0.89 | PTGDR2 (0.69) | PTGDR2CTSGCMA1ARHTT | |
| SCHEMBL4455217 | 0.89 | CTSG (0.75) | PTGDR2CTSGCMA1PDPK1ATM | |
| SCHEMBL5266755 | 0.88 | PTGDR2 (0.64) | PTGDR2CTSGCMA1ARPDPK1 | |
| SCHEMBL14577952 | 0.81 | PTGDR2 (0.67) | PTGDR2CTSGCMA1ARHTT | |
| SCHEMBL9681428 | 0.81 | PTGDR2 (0.71) | PTGDR2HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7036120 | 0.81 | PTGDR2 (0.55) | PTGDR2CTSGCMA1ARHTT | |
| SCHEMBL9699191 | 0.81 | PTGDR2 (0.66) | PTGDR2CTSGCMA1ARL3MBTL1 | |
| SCHEMBL5109787 | 0.80 | PTGDR2 (1.00) | PTGDR2PDPK1ATMKMT2A | |
| SCHEMBL7033870 | 0.79 | PTGDR2 (0.54) | PTGDR2CTSGCMA1ARHTT | |
| SCHEMBL14577943 | 0.79 | PTGDR2 (0.61) | PTGDR2CTSGCMA1ARPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | TEIJIN LIMITED (JP) | 2003-05-01 | — | — | US | disclosed |
| EP-1167360-A9 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-05-15 | — | — | EP | disclosed |
| EP-1167360-A1 | HUMAN CHYMASE INHIBITORS | TEIJIN LIMITED (JP) | 2002-01-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083315-A1 | Human chymase inhibitors | CMA1, CTRL, CPA4 | PTGDR2 2898/4885CTSG 204/4885CMA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.