Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.61 |
| ▸ | NPC1 | O15118 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.61 |
| ▸ | MYC | P01106 | 1/20 | 0.56 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | RAB9A | P51151 | 6/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536926 | 1.00 | KMT2A (0.61) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL11511138 | 0.86 | MYC (0.48) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL27426809 | 0.84 | TRPA1 (0.56) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL4060540 | 0.83 | TRPA1 (0.54) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL4060542 | 0.83 | TRPA1 (0.54) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL187588 | 0.83 | TDP1 (0.55) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL30342247 | 0.83 | TDP1 (0.55) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL28313589 | 0.83 | TDP1 (0.55) | KMT2ANPC1MEN1POLBTRPA1 | |
| SCHEMBL29747008 | 0.81 | MAPK1 (0.53) | KMT2ANPC1MEN1POLBTRPA1 | |
| Hydrogen Sulfide SCHEMBL28338492 | 0.81 | TDP1 (0.53) | KMT2ANPC1MEN1POLBTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9261460-B2 | Real-time nucleic acid detection processes and compositions | ENZO LIFE SCIENCES, INC. (US) | 2016-02-16 | — | — | US | claimed |
| US-20050084920-A1 | Fluorescence assay for measuring the rate of cholesterol ester transfer | MERCK SHARP & DOHME CORP. | 2005-04-21 | — | — | US | claimed |
| EP-1412512-A4 | DETECTION OF RAS MUTATIONS | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2004-04-28 | — | — | EP | claimed |
| EP-1412512-A2 | DETECTION OF RAS MUTATIONS | Ortho-Clinical Diagnostics, Inc. (US) | 2004-04-28 | — | — | EP | claimed |
| WO-2002029005-A2 | DETECTION OF RAS MUTATIONS | ORTHO-CLINICAL DIAGNOSTICS, INC. (US) | 2002-04-11 | — | — | WO | claimed |
| EP-0826780-A1 | Detection of nucleic acids using G-quartets | Becton, Dickinson and Company (US) | 1998-03-04 | — | — | EP | claimed |
| US-5691145-A | OLIGONUCLEOTIDE LABELLED WITH DONOR FLUOROPHORE AND ACCEPTOR DYE; DETECTING CHANGE IN FLUORESCENCE | BECTON, DICKINSON AND COMPANY (US) | 1997-11-25 | — | — | US | claimed |
| US-20220136074-A1 | ISOTHERMAL AMPLIFICATION AND AMBIENT VISUALIZATION IN A SINGLE TUBE FOR THE DETECTION OF SARS-COV-2 USING LOOP-MEDIATED AMPLIFICATION AND CRISPR TECHNOLOGY | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2022-05-05 | — | — | US | disclosed |
| EP-2649202-B1 | NUCLEIC ACID TARGET DETECTION USING A DETECTOR, A PROBE AND AN INHIBITOR | BIO RAD LABORATORIES (US) | 2019-02-20 | — | — | EP | disclosed |
| EP-2896963-B1 | Wound prognosis | WOUNDCHEK LABORATORIES B V (NL) | 2019-01-30 | — | — | EP | disclosed |
| US-9932622-B2 | Wound prognosis | WOUNDCHEK LABORATORIES B.V. (NL) | 2018-04-03 | — | — | US | disclosed |
| US-20170226568-A1 | NUCLEIC ACID TARGET DETECTION USING A DETECTOR, A PROBE AND AN INHIBITOR | BIO-RAD LABORATORIES, INC | 2017-08-10 | — | — | US | disclosed |
| EP-2619316-B1 | ULTRASENSITIVE DETECTION OF BETA HEMOLYTIC STREPTOCOCCUS | WOUNDCHEK LABORATORIES B V (NL) | 2016-12-07 | — | — | EP | disclosed |
| US-5766963-A | IDENTIFYING BIOLOGICALLY ACTIVE MEMBERS BY SCREENING IN BIOASSAYS | PHARMACOPEIA, INC. (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0654093-A4 | DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY. | ABBOTT LAB (US) | 1998-01-07 | — | — | EP | disclosed |
| WO-1997027315-A1 | COMBINATORIAL HYDROXYPROPYLAMINE LIBRARY | PHARMACOPEIA, INC. (US) | 1997-07-31 | — | — | WO | disclosed |
| WO-1997016569-A1 | LAWN ASSAY FOR COMPOUNDS THAT AFFECT ENZYME ACTIVITY OR BIND TO TARGET MOLECULES | PHARMACOPEIA, INC. (US) | 1997-05-09 | — | — | WO | disclosed |
| US-5573907-A | Detecting and amplifying target nucleic acids using exonucleolytic activity | ABBOTT LABORATORIES (US) | 1996-11-12 | — | — | US | disclosed |
| EP-0654093-A1 | DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY | ABBOTT LABORATORIES (US) | 1995-05-24 | — | — | EP | disclosed |
| WO-1994003636-A1 | DETECTING AND AMPLIFYING TARGET NUCLEIC ACIDS USING EXONUCLEOLYTIC ACTIVITY | ABBOTT LABORATORIES (US) | 1994-02-17 | — | — | WO | disclosed |