SCHEMBL4060540

SCHEMBL4060540

CN(C)c1cc(C(=O)O)ccc1/N=N/c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.54
NPC1 O15118 6/20 0.51
MEN1 O00255 4/20 0.51
KMT2A Q03164 4/20 0.51
POLB P06746 2/20 0.51
MYC P01106 1/20 0.48
MAPT P10636 7/20 0.48
RAB9A P51151 5/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
CASP3 P42574 1/20 0.44
SENP8 Q96LD8 1/20 0.44
SENP7 Q9BQF6 1/20 0.44
SENP6 Q9GZR1 1/20 0.44
HCAR3 P49019 1/20 0.43
MAPK1 P28482 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
ALDH1A1 P00352 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
KDM4E B2RXH2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4060542 1.00 TRPA1 (0.54) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL6536926 0.83 KMT2A (0.61) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL703401 0.83 KMT2A (0.61) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL3267905 0.78 MAPT (0.71) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL8854399 0.78 TDP1 (0.61) NPC1MEN1KMT2APOLBMYC
SCHEMBL4650520 0.78 TRPA1 (0.61) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL8854396 0.78 TDP1 (0.61) NPC1MEN1KMT2APOLBMYC
SCHEMBL6740933 0.78 TRPA1 (0.61) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL29032673 0.76 TDP1 (0.60) TRPA1NPC1MEN1KMT2APOLB
SCHEMBL6692609 0.76 TDP1 (0.60) TRPA1NPC1MEN1KMT2APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2091322-B1 CLUMP RECOGNITION ANIMAL LITTER CHURCH & DWIGHT CO INC (US) 2019-08-14 EP disclosed
US-20090325304-A1 Mammalian Disease Detection System NULLODOR USA LLC 2009-12-31 US disclosed
US-20090255478-A1 CLUMP RECOGNITION ANIMAL LITTER CHURCH & DWIGHT CO., INC. 2009-10-15 US disclosed
EP-2091322-A2 CLUMP RECOGNITION ANIMAL LITTER Church & Dwight Co., Inc. (US) 2009-08-26 EP disclosed
WO-2008064201-A2 CLUMP RECOGNITION ANIMAL LITTER CHURCH & DWIGHT CO., INC. (US) 2008-05-29 WO disclosed
EP-1620120-A2 LONG ACTING BIOLOGICALLY ACTIVE CONJUGATES Sequoia Pharmaceuticals (US) 2006-02-01 EP disclosed
WO-2004085505-A2 LONG ACTING BIOLOGICALLY ACTIVE CONJUGATES SEQUOIA PHARMACEUTICALS, INC. (US) 2004-10-07 WO disclosed
WO-1995005073-A1 IMPROVED COMPOSITIONS FOR USE AS DIAGNOSTIC ANIMAL LITTER AND METHODS FOR THEIR PREPARATION ENGELHARD CORPORATION (US) 1995-02-23 WO disclosed
US-5371054-A Uncalcined clay substrate having specified calcium oxide and attapulgite content in combination with chemical pH indicator ENGELHARD CORPORATION (US) 1994-12-06 US disclosed