SCHEMBL7034471

SCHEMBL7034471

O=C(NC1CCNCC1)c1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KHK P50053 1/20 0.57
ALDH1A1 P00352 1/20 0.52
NPC1 O15118 1/20 0.51
RAB9A P51151 1/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
P2RY14 Q15391 1/20 0.49
MMP2 P08253 1/20 0.49
ANPEP P15144 1/20 0.49
SMYD3 Q9H7B4 3/20 0.49
HDAC3 O15379 1/20 0.49
HDAC4 P56524 1/20 0.49
HDAC1 Q13547 1/20 0.49
HDAC7 Q8WUI4 1/20 0.49
HDAC2 Q92769 1/20 0.49
HDAC10 Q969S8 1/20 0.49
HDAC11 Q96DB2 1/20 0.49
HDAC8 Q9BY41 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49
HDAC9 Q9UKV0 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28975685 0.89 NPC1 (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL30583812 0.89 NPC1 (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL30583813 0.89 NPC1 (0.57) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL9835734 0.85 KMT2A (0.66) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL14110292 0.84 KMT2A (0.63) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL11493127 0.83 KMT2A (0.55) KHKALDH1A1MEN1KMT2APOLB
SCHEMBL28291009 0.81 KHK (0.49) KHKALDH1A1NPC1RAB9APOLB
SCHEMBL30583809 0.81 MMP2 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL30583808 0.81 MMP2 (0.56) ALDH1A1NPC1RAB9AMEN1KMT2A
SCHEMBL2716593 0.80 ALDH1A1 (0.60) ALDH1A1NPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1052248-B1 Process for the preparation of aqueous solutions of diazonium salts CLARIANT GMBH (DE) 2003-03-19 EP disclosed
US-6207809-B1 CATALYTIC HYDROGENATION USING THE CORRESPONDING NITRO COMPOUND CLARIANT GMBH (DE) 2001-03-27 US disclosed
EP-1052248-A1 Process for the preparation of aqueous solutions of diazonium salts Clariant GmbH (DE) 2000-11-15 EP disclosed