Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27753252 | 0.86 | EGFR (0.37) | CYP3A4 | |
| SCHEMBL27395877 | 0.84 | EGFR (0.36) | CYP3A4 | |
| SCHEMBL2125263 | 0.70 | GUSB (0.31) | — | |
| SCHEMBL29429673 | 0.70 | GUSB (0.31) | — | |
| SCHEMBL707871 | 0.66 | CYP3A4 (0.71) | CYP3A4 | |
| SCHEMBL5924182 | 0.65 | HTT (0.49) | — | |
| SCHEMBL4479696 | 0.65 | HRH4 (0.54) | — | |
| Hydrochloric Acid SCHEMBL7080808 | 0.65 | CYP3A4 (0.69) | CYP3A4 | |
| SCHEMBL3833609 | 0.64 | F10 (0.47) | CYP3A4 | |
| SCHEMBL5924458 | 0.64 | TUBB4A (0.56) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290004-A1 | METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6365359-B1 | IDENTIFYING PRP PHARMACORE BY DETERMINING FUNCTIONAL RESIDUES OF PROTEIN INVOLVED IN COMPLEX INTERACTIONS, DEVELOPING THREE DIMENSIONAL STRUCTURES, COMPARING THEM WITH OTHER COMPOUNDS AND IDENTIFYING COMPOUNDS CONSISTENT WITH BINDING TO PROTEIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-02 | — | — | US | disclosed |
| WO-2001087911-A1 | METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-22 | — | — | WO | disclosed |