Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035231 | 0.84 | CYP3A4 (0.33) | CYP3A4 | |
| SCHEMBL9192389 | 0.72 | SMN1; SMN2 (0.52) | EGFRCYP3A4 | |
| SCHEMBL707871 | 0.66 | CYP3A4 (0.71) | CYP3A4 | |
| Hydrochloric Acid SCHEMBL7080808 | 0.65 | CYP3A4 (0.69) | CYP3A4 | |
| SCHEMBL11025980 | 0.64 | MEN1 (0.43) | — | |
| SCHEMBL3833609 | 0.64 | F10 (0.47) | CYP3A4 | |
| SCHEMBL5924458 | 0.64 | TUBB4A (0.56) | CYP3A4 | |
| SCHEMBL4517474 | 0.62 | METAP2 (0.39) | CYP3A4 | |
| SCHEMBL19207406 | 0.62 | KDM4E (0.35) | — | |
| SCHEMBL4264509 | 0.62 | HTT (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1081034-C | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 2002-03-20 | — | — | CN | claimed |
| CN-1192903-A | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 1998-09-16 | — | — | CN | claimed |
| CN-109908350-A | Application of the Na-ion channel blocker in preparation treatment melanoma drug | 自然资源部第三海洋研究所 | 2019-06-21 | — | — | CN | disclosed |
| CN-101450056-B | New use of sodium ion channel blocker in treating biology drug resistance of antibiotic | JIANGSU HONGJINTIAN PHARMACEUTICAL CO LTD | 2013-04-24 | — | — | CN | disclosed |
| CN-101513408-A | Novel application of preparation of diguanidino-prine derivatives in improving drug effects of anti-cancer drugs | PING XIONG (CN) | 2009-08-26 | — | — | CN | disclosed |
| CN-101485663-A | Novel use of sodium ion channel antagonist compound in improving quality of human sleeping | SHENZHEN HONGJINTIAN BIOTECHNO (CN) | 2009-07-22 | — | — | CN | disclosed |
| CN-101468013-A | Novel use of biguanide-based purine ring derivates in improving medicament effect of analgesia medicament | FANGLONG QIU (CN) | 2009-07-01 | — | — | CN | disclosed |
| CN-101450056-A | New use of sodium ion channel blocker in treating biology drug resistance of antibiotic | SHENZHEN HONGJINTIAN BIOTECHNO (CN) | 2009-06-10 | — | — | CN | disclosed |
| CN-101422463-A | New use of sodium-ion channel blocker compound in clearing biosome endotoxin | SHENZHEN HONGJINTIAN BIOTECHNO (CN) | 2009-05-06 | — | — | CN | disclosed |
| CN-1081034-C | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 2002-03-20 | — | — | CN | disclosed |
| CN-1081034-C | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 2002-03-20 | — | — | CN | disclosed |
| CN-1081034-C | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 2002-03-20 | — | — | CN | disclosed |
| CN-1192903-A | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 1998-09-16 | — | — | CN | disclosed |
| CN-1192903-A | Medicine of diguanidino-prine-hydride compounds for giving up drug-taking | PAN XINFU (CN) | 1998-09-16 | — | — | CN | disclosed |