Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27337608 | 0.81 | HDAC1 (0.42) | FDPSHDAC1HDAC6 | |
| SCHEMBL27930861 | 0.81 | FDPS (0.38) | FDPSHDAC1HDAC6 | |
| SCHEMBL27747628 | 0.77 | FDPS (0.35) | FDPSHDAC1HDAC6 | |
| SCHEMBL5828209 | 0.75 | FDPS (0.40) | FDPSHDAC1HDAC6 | |
| SCHEMBL3021750 | 0.72 | FDPS (0.40) | FDPSHDAC1HDAC6 | |
| SCHEMBL9356692 | 0.72 | FDPS (0.40) | FDPSHDAC1HDAC6 | |
| SCHEMBL10774226 | 0.71 | FDPS (0.41) | FDPSHDAC1HDAC6 | |
| SCHEMBL2126857 | 0.70 | HDAC1 (0.49) | FDPSHDAC1HDAC6 | |
| SCHEMBL20979882 | 0.70 | HDAC1 (0.43) | FDPSHDAC1HDAC6 | |
| Niacinamide SCHEMBL28587079 | 0.69 | SIRT2 (0.51) | HDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1290004-A1 | METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6365359-B1 | IDENTIFYING PRP PHARMACORE BY DETERMINING FUNCTIONAL RESIDUES OF PROTEIN INVOLVED IN COMPLEX INTERACTIONS, DEVELOPING THREE DIMENSIONAL STRUCTURES, COMPARING THEM WITH OTHER COMPOUNDS AND IDENTIFYING COMPOUNDS CONSISTENT WITH BINDING TO PROTEIN | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2002-04-02 | — | — | US | disclosed |
| WO-2001087911-A1 | METHOD OF IDENTIFYING CRITICAL POINTS WITHIN PROTEIN-PROTEIN INTERACTIONS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2001-11-22 | — | — | WO | disclosed |