Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HBB | P68871 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9356692 | 0.81 | FDPS (0.40) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL3021750 | 0.81 | FDPS (0.40) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL3421967 | 0.81 | FDPS (0.46) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL27930861 | 0.78 | FDPS (0.38) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL27337608 | 0.78 | HDAC1 (0.42) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL5041084 | 0.77 | FDPS (0.37) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL5436672 | 0.77 | FDPS (0.37) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL4859275 | 0.77 | FDPS (0.37) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL2789824 | 0.75 | CYP1A2 (0.36) | FDPSHDAC1HDAC6LTA4HALDH1A1 | |
| SCHEMBL7035233 | 0.75 | FDPS (0.37) | FDPSHDAC1HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112912378-B | Hydrazinopurine compounds and triazolopurine compounds for inhibiting xanthine oxidase | 泰拉强石株式会社 | 2023-09-12 | — | — | CN | claimed |
| US-20210347778-A1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | TERA STONE CO., LTD (JP) | 2021-11-11 | — | — | US | claimed |
| EP-3845535-A1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | Tera Stone Co., Ltd (JP) | 2021-07-07 | — | — | EP | claimed |
| CN-112912378-A | Hydrazinopurine compounds and triazolopurine compounds for inhibiting xanthine oxidase | 泰拉强石株式会社 | 2021-06-04 | — | — | CN | claimed |
| WO-2020045558-A1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | テラ・ストーン株式会社 | 2020-03-05 | — | — | WO | claimed |
| US-7034016-B2 | 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2006-04-25 | — | — | US | claimed |
| EP-1198464-B1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2003-10-08 | — | — | EP | claimed |
| US-20030060627-A1 | 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2003-03-27 | — | — | US | claimed |
| EP-1198464-A1 | 8-PHENYL-6,9-DIHYDRO- 1,2,4]TRIAZOLO 3,4- i i /i ]PURIN-5-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2002-04-24 | — | — | EP | claimed |
| WO-2001007441-A1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2001-02-01 | — | — | WO | claimed |
| EP-3845535-B1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | TERA STONE CO LTD (JP) | 2024-06-26 | — | — | EP | disclosed |
| CN-112912378-B | Hydrazinopurine compounds and triazolopurine compounds for inhibiting xanthine oxidase | 泰拉强石株式会社 | 2023-09-12 | — | — | CN | disclosed |
| CN-112912378-B | Hydrazinopurine compounds and triazolopurine compounds for inhibiting xanthine oxidase | 泰拉强石株式会社 | 2023-09-12 | — | — | CN | disclosed |
| JP-2023071839-A | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | テラ・ストーン株式会社 | 2023-05-23 | — | — | JP | disclosed |
| US-20210347778-A1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | TERA STONE CO., LTD (JP) | 2021-11-11 | — | — | US | disclosed |
| US-7034016-B2 | 8-phenyl-6,9-dihydro-[1,2,4]triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2006-04-25 | — | — | US | disclosed |
| EP-1198464-B1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA SA (ES) | 2003-10-08 | — | — | EP | disclosed |
| US-20030060627-A1 | 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives | ALMIRALL PRODESFARMA, S.A. (ES) | 2003-03-27 | — | — | US | disclosed |
| EP-1198464-A1 | 8-PHENYL-6,9-DIHYDRO- 1,2,4]TRIAZOLO 3,4- i i /i ]PURIN-5-ONE DERIVATIVES | Almirall Prodesfarma, S.A. (ES) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001007441-A1 | 8-PHENYL-6,9-DIHYDRO-[1,2,4]TRIAZOLO[3,4-i]PURIN-5-ONE DERIVATIVES | ALMIRALL PRODESFARMA S.A. (ES) | 2001-02-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030060627-A1 | 8-Phenyl-6, 9-dihydro-[1,2,4] triazolo[3,4-i]purin-5-one derivatives | HYOU1, CHN2, PURB | FDPS 4023/4885HDAC1 1248/4885HDAC6 2147/4885 |
| US-20210347778-A1 | HYDRAZINOPURINE COMPOUND AND TRIAZOLOPURINE COMPOUND FOR INHIBITING XANTHINE OXIDASE | XDH, HPRT1, TPMT | FDPS 855/4885HDAC1 327/4885HDAC6 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.