Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL7035528

NN=Cc1ccc(C(=O)Nc2ccc3c(c2)CCN(CC(=O)O)C3=O)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 19/20 0.67
ITGA2B P08514 19/20 0.67
ITGA2 P17301 3/20 0.49
SLC2A1 P11166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL7035525 0.86 ITGB3 (0.89) ITGB3ITGA2BITGA2
Trifluoroacetic Acid SCHEMBL7116507 0.83 ITGB3 (0.50) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7025720 0.83 ITGB3 (0.62) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7025929 0.82 ITGB3 (0.62) ITGB3ITGA2B
SCHEMBL7345980 0.80 ITGB3 (1.00) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7029868 0.79 ITGB3 (0.69) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7032204 0.77 ITGB3 (0.56) ITGB3ITGA2B
Trifluoroacetic Acid SCHEMBL7030491 0.76 ITGB3 (0.57) ITGB3ITGA2B
SCHEMBL7444173 0.75 ITGB3 (0.72) ITGB3ITGA2BITGA2
Trifluoroacetic Acid SCHEMBL8182682 0.73 ITGB3 (0.68) ITGB3ITGA2BITGA2SLC2A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030135045-A1 Glycoprotein IIb/IIIa antagonists FISHER MATTHEW J (US) 2003-07-17 US disclosed
US-6472405-B1 Glycoprotein IIB/IIIA antagonists ELI LILLY AND COMPANY 2002-10-29 US disclosed
EP-0635492-B1 Glycoprotein IIb/IIIa antagonists LILLY CO ELI (US) 2002-10-02 EP disclosed
US-6137002-A USEFUL FOR PREVENTION OF THROMBOSIS; FOR TREATING ATHEROSCLEROSIS AND ARTERIOSCLEROSIS, ACUTE MYOCARDIAL INFARCTION, CHRONIC STABLE ANGINA, UNSTABLE ANGINA, TRANSIENT ISCHEMIC ATTACKS AND STROKES, PERIPHERAL VASCULAR DISEASE, ELI LILLY AND COMPANY (US) 2000-10-24 US disclosed
US-5618843-A INHIBIT PLATELET AGGREGATION ELI LILLY AND COMPANY (US) 1997-04-08 US disclosed
EP-0635492-A1 Glycoprotein IIb/IIIa antagonists ELI LILLY AND COMPANY (US) 1995-01-25 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030135045-A1 Glycoprotein IIb/IIIa antagonists GP6, TBXA2R, ITGA2B ITGB3 14/4885ITGA2B 3/4885ITGA2 8/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.