Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | CRHBP | P24387 | 2/20 | 0.31 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20594438 | 0.78 | AKR1B1 (0.34) | — | |
| SCHEMBL20975606 | 0.77 | NOTUM (0.34) | LMNAHTT | |
| SCHEMBL7971051 | 0.76 | OXTR (0.39) | OXTRMAOAMAOB | |
| Hydrochloric Acid SCHEMBL27471846 | 0.74 | OXTR (0.38) | OXTRLMNAMAOAMAOB | |
| SCHEMBL236649 | 0.71 | OXTR (0.42) | OXTRSMN1; SMN2LMNACRHBPCRHR2 | |
| SCHEMBL1987212 | 0.71 | HSD17B3 (0.36) | LMNA | |
| SCHEMBL14182625 | 0.70 | OXTR (0.39) | OXTRMAOAMAOB | |
| SCHEMBL12203619 | 0.69 | ADRA2A (0.38) | — | |
| SCHEMBL28644317 | 0.68 | OXTR (0.39) | OXTRSMN1; SMN2LMNACRHBPCRHR2 | |
| SCHEMBL23042905 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1554651-A | Benzopyrans and benzothiopyrans, pharmaceutical compositions containing them and process for their preparation | Ĭ��ר���ɷ�����˾ | 2004-12-15 | — | — | CN | claimed |
| US-6596758-B1 | Treatment of dislipidaemias, atherosclerosis and diabetes, to pharmaceutical compositions comprising them and to processes allowing the preparation of these compounds. | MERCK PATENT GMBH (DE) | 2003-07-22 | — | — | US | claimed |
| EP-1140893-B1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2003-03-05 | — | — | EP | claimed |
| EP-1140893-B1 | BENZOPYRANS AND BENZOXEPINES, PHARMACEUTICAL COMPOSITIONS COMPRISING THEM AND PREPARATION PROCESS | MERCK PATENT GMBH (DE) | 2003-03-05 | — | — | EP | disclosed |