Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | HPGD | P15428 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7040964 | 0.79 | HSD17B10 (0.64) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL14582034 | 0.77 | TLR8 (0.55) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL23552408 | 0.77 | KDM4E (0.81) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6844740 | 0.77 | KDM4E (0.67) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL1020149 | 0.75 | HTT (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29979980 | 0.75 | HTT (0.43) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL2147607 | 0.74 | KDM4E (0.59) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL6143071 | 0.73 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL29076183 | 0.73 | KDM4E (0.66) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL30581235 | 0.73 | KDM4E (1.00) | KDM4EALDH1A1MAPTHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6221343-B1 | Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2001-04-24 | — | — | US | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |