Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7035923 | 0.79 | KDM4E (0.59) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL30410670 | 0.78 | HSD17B10 (1.00) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL25454233 | 0.78 | HSD17B10 (1.00) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL14582034 | 0.78 | TLR8 (0.55) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL1020149 | 0.76 | HTT (0.43) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL29979980 | 0.76 | HTT (0.43) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL15568473 | 0.72 | HSD17B10 (0.76) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL927722 | 0.72 | HPGD (0.39) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL8104229 | 0.72 | ALDH1A1 (0.42) | HSD17B10TSHRLMNAALDH1A1MAPT | |
| SCHEMBL1520867 | 0.71 | L3MBTL1 (0.67) | HSD17B10TSHRLMNAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1028120-B1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | OREAL (FR) | 2003-03-19 | — | — | EP | disclosed |
| US-6221343-B1 | Benzimidazole/benzofuryl-benzazole silicon compounds and UV-photoprotective compositions comprised thereof | SOCIETE L'OREAL S.A. (FR) | 2001-04-24 | — | — | US | disclosed |
| EP-1028120-A1 | Organosilicon compounds with N-substituted benzimidazole-benzazole or benzofuranyl-benzazole groups, sunscreen compositions containing these compounds and their use | L'OREAL (FR) | 2000-08-16 | — | — | EP | disclosed |