Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 10/20 | 0.33 |
| ▸ | CNR2 | P34972 | 10/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27097050 | 0.80 | RIPK1 (0.39) | LMNAPOLBCNR1CNR2 | |
| SCHEMBL16407995 | 0.77 | POLB (0.37) | POLBL3MBTL1CNR1CNR2ATM | |
| SCHEMBL29261236 | 0.75 | POLB (0.40) | LMNAPOLBKMT2AMEN1ALDH1A1 | |
| SCHEMBL6852859 | 0.74 | HTT (0.44) | HTTLMNAPOLBKMT2AMEN1 | |
| SCHEMBL27082329 | 0.73 | CA2 (0.40) | POLBKMT2AMEN1ALDH1A1CNR1 | |
| SCHEMBL4173669 | 0.73 | POLB (0.35) | POLBCNR1CNR2ATMNPC1 | |
| SCHEMBL6578326 | 0.72 | — | — | |
| SCHEMBL6519888 | 0.72 | — | — | |
| SCHEMBL291139 | 0.71 | CNR1 (0.36) | POLBALDH1A1CNR1CNR2ATM | |
| SCHEMBL25118452 | 0.71 | MAPT (0.43) | KMT2AMEN1MAPTL3MBTL1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1476455-A1 | PARTIAL AND FULL AGONISTS OF A sb 1 /sb ADENOSINE RECEPTORS | CV THERAPEUTICS, INC. (US) | 2004-11-17 | — | — | EP | disclosed |
| WO-2003070739-A1 | PARTIAL AND FULL AGONISTS OF A1 ADENOSINE RECEPTORS | CV THERAPEUTICS, INC. (US) | 2003-08-28 | — | — | WO | disclosed |
| US-6596798-B1 | method for forming a functionalized polymer comprising the steps of providing a living lithium polymer; and terminating the living lithium polymer with an oxazoline compound according to the following formula (I): | BRIDGESTONE CORPORATION (JP) | 2003-07-22 | — | — | US | disclosed |
| US-20030125477-A1 | Preparation of low hysteresis rubber by reacting a lithium polymer with oxazoline compounds | BRIDGESTONE CORPORATION (JP) | 2003-07-03 | — | — | US | disclosed |