Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702921 | 0.78 | GRM5 (0.32) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL14136807 | 0.75 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL14136800 | 0.74 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL1069018 | 0.74 | LMNA (0.46) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL15154610 | 0.74 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL16095811 | 0.74 | MEN1 (0.38) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL20480716 | 0.73 | PLA2G4A (0.34) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL4442591 | 0.73 | ADORA1 (0.49) | MEN1KMT2AL3MBTL1 | |
| SCHEMBL28963247 | 0.72 | PTGS1 (0.30) | — | |
| SCHEMBL4962084 | 0.72 | MEN1 (0.39) | MEN1KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772502-B2 | Alkylsulfinyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2014-07-08 | — | — | US | disclosed |
| US-20120108591-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | ROMARK LABORATORIES, L.C. | 2012-05-03 | — | — | US | disclosed |
| US-8124632-B2 | Alkylsulfonyl-substituted thiazolide compounds | ROMARK LABORATORIES, L.C. (US) | 2012-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108591-A1 | ALKYLSULFINYL-SUBSTITUTED THIAZOLIDE COMPOUNDS | HAVCR2, EIF2AK2, HCCS | MEN1 4047/4885KMT2A 4262/4885L3MBTL1 1096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.