SCHEMBL70367

SCHEMBL70367

O=C(CC(F)(F)F)c1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 3/20 0.56
MAPK1 P28482 2/20 0.56
MAPT P10636 2/20 0.56
TDP1 Q9NUW8 2/20 0.56
MEN1 O00255 2/20 0.56
CYP3A4 P08684 2/20 0.56
HPGD P15428 2/20 0.56
KMT2A Q03164 2/20 0.56
KDM4E B2RXH2 1/20 0.56
ALOX15 P16050 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
ALDH1A1 P00352 5/20 0.52
GSK3B P49841 2/20 0.52
PTPN1 P18031 2/20 0.52
HIF1A Q16665 2/20 0.52
TRPA1 O75762 1/20 0.52
POLB P06746 2/20 0.51
NPSR1 Q6W5P4 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Sulfide SCHEMBL28313848 0.98 TDP1 (0.54) CES1MAPK1MAPTTDP1MEN1
Acetophenone SCHEMBL571089 0.90 POLB (0.49) CES1MAPK1MAPTTDP1MEN1
SCHEMBL396689 0.88 PTPN1 (0.48) CES1MAPK1MAPTTDP1MEN1
SCHEMBL27839718 0.88 SMN1; SMN2 (0.58) MAPTHPGDKDM4ESMN1; SMN2ALDH1A1
Acetoacetic Acid SCHEMBL27781228 0.86 KMT2A (0.47) CES1MAPK1MAPTTDP1MEN1
Tetrahydrofuran SCHEMBL28151584 0.86 KMT2A (0.50) CES1MAPK1MAPTTDP1MEN1
SCHEMBL5865907 0.86 KMT2A (0.46) CES1MAPK1MAPTTDP1MEN1
SCHEMBL28352832 0.83 CES1 (0.52) CES1MAPK1MAPTTDP1MEN1
SCHEMBL16439919 0.83 POLB (0.53) CES1MAPK1MAPTTDP1MEN1
SCHEMBL28741012 0.83 ALDH1A1 (0.54) CES1MAPK1MAPTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 883 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12466787-B2 Process for synthesis of high purity 1-[3-(trifluoromethyl)phenyl]ethanone oxime LAXMI ORGANIC INDUSTRIES LTD (IN) 2025-11-11 US claimed
CN-119684071-A Para-terphenyl derivative and synthesis method thereof 湖南大学 2025-03-25 CN claimed
CN-119680592-A Non-metal P doped ZnIn2S4Preparation method and application of photocatalyst 重庆第二师范学院 2025-03-25 CN claimed
CN-119463910-A Mesophase pitch and preparation method thereof 中国石油化工股份有限公司 2025-02-18 CN claimed
CN-118459420-A Thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-118459422-A Thiazole thiazolinone compound containing multiple halogen atoms and preparation method thereof 南京工业大学 2024-08-09 CN claimed
CN-115521946-B TiO (titanium dioxide)xMethod for synthesizing (R) -1- [3, 5-di (trifluoromethyl) ] phenethyl alcohol by using base photo-enzyme catalyst 浙江玖世生物科技有限公司 2024-06-21 CN claimed
CN-116082269-B 1,3, 4-Oxazoline compound containing trifluoromethyl quaternary carbon center and preparation method thereof 盐城工学院 2024-06-21 CN claimed
CN-114456098-B Preparation method of medicine Ai Shali ketone for treating diabetic nephropathy 大连理工大学 2024-06-14 CN claimed
CN-115386604-B Method for catalyzing and synthesizing R-3,5-BTPE by using infrared light driven carbon quantum dot based photo-enzyme catalyst 浙江玖世生物科技有限公司 2024-05-31 CN claimed
CN-1247512-C Process for preparing trifluoromethyl acetophenone compound UNIV ZHEJIANG POLYTECHNIC (CN) 2006-03-29 CN claimed
CN-1626563-A Epoxy resin of containing fluorine, ramification, preparation method and application CHINESE ACAD INST CHEMISTRY (CN) 2005-06-15 CN claimed
CN-1605587-A Fluorine-containing aromatic organic tetracarboxylic dianhydride and preparation method and application thereof CHINESE ACAD INST CHEMISTRY (CN) 2005-04-13 CN claimed
CN-1587246-A Process for preparing trifluoromethyl acetophenone compound UNIV ZHEJIANG POLYTECHNIC (CN) 2005-03-02 CN claimed
EP-1240127-A1 PROCESS FOR THE PRODUCTION OF TRIFLUOROMETHYLACETOPHENONES Bayer Aktiengesellschaft (DE) 2002-09-18 EP claimed
WO-2001044152-A1 PROCESS FOR THE PRODUCTION OF TRIFLUOROMETHYLACETOPHENONES BAYER AKTIENGESELLSCHAFT (DE) 2001-06-21 WO claimed
US-5969188-A Process for producing trifluoromethylacetophenones NIPA HARDWICKE, INC. (US) 1999-10-19 US claimed
US-4617401-A ANTISPASMODIC AGENTS, VASODILATORS SUNTORY LTD. (JP) 1986-10-14 US claimed
EP-0039903-B1 8-SUBSTITUTED PYRROLIZIDINES AND QUATERNARY AMMONIUM SALTS THEREOF SUNTORY KABUSHIKI KAISHA (JP) 1986-04-09 EP claimed
EP-0039903-A2 8-Substituted pyrrolizidines and quaternary ammonium salts thereof SUNTORY KABUSHIKI KAISHA (JP) 1981-11-18 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12466787-B2 Process for synthesis of high purity 1-[3-(trifluoromethyl)phenyl]ethanone oxime GRIK1, KCNK4, GRIK4 CES1 3423/4885MAPK1 123/4885MAPT 3982/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.