Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | PCSK9 | Q8NBP7 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 3/20 | 0.36 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1779630 | 0.91 | HTR6 (0.44) | L3MBTL1PTGDR2HTR6GSK3BEED | |
| SCHEMBL1777841 | 0.91 | L3MBTL1 (0.41) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL1777351 | 0.86 | KDM4E (0.45) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL1779371 | 0.86 | PSEN1 (0.44) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL1778220 | 0.86 | L3MBTL1 (0.40) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL6140206 | 0.86 | L3MBTL1 (0.47) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL12606428 | 0.85 | L3MBTL1 (0.40) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL1779250 | 0.85 | L3MBTL1 (0.40) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 | |
| SCHEMBL1777336 | 0.85 | L3MBTL1 (0.46) | L3MBTL1PCSK9PTGDR2CCNE1CDK2 | |
| SCHEMBL1778092 | 0.84 | L3MBTL1 (0.39) | L3MBTL1PCSK9PTGDR2HTR6CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397360-A1 | AZAINDOLES | Aventis Pharma Limited (GB) | 2004-03-17 | — | — | EP | disclosed |
| WO-2003000688-A1 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2003-01-03 | — | — | WO | disclosed |
| EP-1263759-A2 | AZAINDOLES | Aventis Pharma Limited (GB) | 2002-12-11 | — | — | EP | disclosed |
| WO-2001047922-A2 | AZAINDOLES | AVENTIS PHARMA LIMITED (GB) | 2001-07-05 | — | — | WO | disclosed |