SCHEMBL7037151

SCHEMBL7037151

C1=COON=C1.O=C1NCc2ccccc21

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.60
CA9 Q16790 1/20 0.60
PARP1 P09874 3/20 0.42
PDPK1 O15530 1/20 0.41
PARP10 Q53GL7 1/20 0.41
PARP11 Q9NR21 1/20 0.41
CLK4 Q9HAZ1 4/20 0.40
DYRK1B Q9Y463 3/20 0.40
NTRK2 Q16620 2/20 0.40
TYRO3 Q06418 1/20 0.40
AURKA O14965 3/20 0.38
KDR P35968 3/20 0.38
GRM5 P41594 2/20 0.38
MAP3K9 P80192 1/20 0.35
MAP3K11 Q16584 1/20 0.35
TDP2 O95551 1/20 0.35
CASP3 P42574 1/20 0.35
CASP7 P55210 1/20 0.35
CASP9 P55211 1/20 0.35
CASP6 P55212 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL515745 0.83 CA12 (0.37) CA12CA9
SCHEMBL14896 0.78 CA12 (1.00) CA12CA9PARP1PDPK1PARP10
SCHEMBL4818277 0.78 CA12 (1.00) CA12CA9PARP1PDPK1PARP10
SCHEMBL29355184 0.78 CA12 (1.00) CA12CA9PARP1PDPK1PARP10
Fluorene SCHEMBL28029875 0.77 MAOA (0.39) CLK4DYRK1BPIM1ROCK1FLT3
Anthraquinone SCHEMBL27563327 0.76 MEN1 (0.46) TDP2CASP3CASP7TSHR
SCHEMBL8213864 0.76 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Water SCHEMBL19462837 0.76 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Hydrochloric Acid SCHEMBL5046932 0.76 CA12 (0.95) CA12CA9PARP1PDPK1PARP10
Water SCHEMBL19462706 0.76 CA12 (0.95) CA12CA9PARP1PDPK1PARP10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002094942-A9 METHOD OF PURIFYING POLYCYCLIC DYES OPTIVA INC (US) 2003-04-10 WO disclosed
US-4866113-A COLORING POLYMERS SANDOZ LTD. (CH) 1989-09-12 US disclosed
US-4838943-A Compounds useful as pigments containing one or more 2,2,6,6-tetraalkylpiperidine groups SANDOZ LTD. (CH) 1989-06-13 US disclosed