Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA7 | P43166 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | APAF1 | O14727 | 1/20 | 0.47 |
| ▸ | TDP2 | O95551 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646108 | 0.91 | PTPN1 (0.51) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL7646703 | 0.91 | PTPN1 (0.51) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL27555709 | 0.83 | TSHR (0.70) | MEN1KMT2ATSHRCA1CA2 | |
| Terephthalic Acid SCHEMBL8811649 | 0.83 | TSHR (0.70) | MEN1KMT2ATSHRCA1CA2 | |
| Terephthalic Acid SCHEMBL4349174 | 0.83 | TSHR (0.70) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL63466 | 0.83 | TSHR (0.70) | MEN1KMT2ATSHRCA1CA2 | |
| Terephthalic Acid SCHEMBL18394717 | 0.83 | TSHR (0.70) | MEN1KMT2ATSHRCA1CA2 | |
| SCHEMBL7526018 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2ATSHRTDP1CACNA1B | |
| SCHEMBL7526004 | 0.82 | ALDH1A1 (0.52) | MEN1KMT2ATSHRTDP1CACNA1B | |
| Hydrochloric Acid SCHEMBL296016 | 0.81 | TSHR (0.67) | MEN1KMT2ATSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
| WO-2001094295-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | MEN1 2354/4885KMT2A 3788/4885TSHR 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.