Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9098471 | 1.00 | NOTUM (0.58) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL9096918 | 0.93 | NOTUM (0.65) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL7646207 | 0.91 | NOTUM (0.50) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL7646103 | 0.91 | NOTUM (0.50) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL7646203 | 0.91 | NOTUM (0.50) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL4611523 | 0.90 | TSHR (0.63) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL2467203 | 0.88 | HTT (0.64) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL9094961 | 0.88 | KMT2A (0.56) | HTTTSHRKMT2AKDM4EMEN1 | |
| SCHEMBL30182553 | 0.85 | NOTUM (0.60) | NOTUMHTTTSHRKMT2AKDM4E | |
| SCHEMBL7526014 | 0.84 | ALDH1A1 (0.44) | NOTUMHTTTSHRKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1289936-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2003-03-12 | — | — | EP | disclosed |
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | TELIK, INC. | 2002-03-14 | — | — | US | disclosed |
| WO-2001094295-A1 | SUBSTITUTED STILBENES AS GLUCOSE UPTAKE ENHANCERS | TELIK, INC. (US) | 2001-12-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032218-A1 | Substituted stilbenes as glucose uptake enhancers | SLC2A1, SLC2A8, SLC2A2 | NOTUM 3584/4885HTT 3240/4885TSHR 858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.