Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | XDH | P47989 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646103 | 1.00 | NOTUM (0.50) | NOTUMPTPN1ALDH1A1APPNPC1 | |
| SCHEMBL7646203 | 1.00 | NOTUM (0.50) | NOTUMPTPN1ALDH1A1APPNPC1 | |
| SCHEMBL7533131 | 0.94 | NOTUM (0.55) | NOTUMPTPN1ALDH1A1APPNPC1 | |
| SCHEMBL7533139 | 0.94 | NOTUM (0.55) | NOTUMPTPN1ALDH1A1APPNPC1 | |
| SCHEMBL7526014 | 0.93 | ALDH1A1 (0.44) | NOTUMPTPN1ALDH1A1APPNPC1 | |
| SCHEMBL7646483 | 0.92 | KMT2A (0.55) | NOTUMPTPN1ALDH1A1NPC1LMNA | |
| SCHEMBL7526766 | 0.92 | KMT2A (0.55) | NOTUMPTPN1ALDH1A1NPC1LMNA | |
| SCHEMBL7646488 | 0.92 | KMT2A (0.55) | NOTUMPTPN1ALDH1A1NPC1LMNA | |
| SCHEMBL9098471 | 0.91 | NOTUM (0.58) | NOTUMALDH1A1NPC1LMNAHPGD | |
| SCHEMBL7037523 | 0.91 | NOTUM (0.58) | NOTUMALDH1A1NPC1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |