Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.49 |
| ▸ | PLK1 | P53350 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 3/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 2/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038115 | 0.99 | IGF2BP2 (0.50) | IGF2BP2NPC1RAB9AKMT2AACMSD | |
| Lithium Ion SCHEMBL7038144 | 0.88 | PPARG (0.61) | NPC1RAB9AKMT2AACMSDHDAC1 | |
| SCHEMBL7038969 | 0.81 | DHODH (0.50) | IGF2BP2NPC1RAB9AACMSDHDAC1 | |
| SCHEMBL7035247 | 0.80 | DHODH (0.51) | IGF2BP2NPC1RAB9AACMSDHDAC1 | |
| SCHEMBL7038142 | 0.76 | IGF2BP2 (0.54) | IGF2BP2NPC1RAB9AKMT2AACMSD | |
| SCHEMBL7040190 | 0.76 | PPARG (0.56) | IGF2BP2NPC1RAB9AKMT2AHDAC1 | |
| SCHEMBL6351486 | 0.75 | KCNK2 (0.73) | NPC1RAB9AKMT2APLK1SERPINE1 | |
| SCHEMBL7038671 | 0.75 | PPARG (0.78) | NPC1RAB9AKMT2AACMSDACLY | |
| SCHEMBL16496601 | 0.75 | SERPINE1 (0.75) | IGF2BP2KMT2ASERPINE1PPARGPPARA | |
| SCHEMBL2274927 | 0.75 | ACLY (0.63) | IGF2BP2NPC1RAB9AKMT2AHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
| WO-2003004458-A1 | NEW COMPOUNDS | BIOVITRUM AB (SE) | 2003-01-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | IGF2BP2 1574/4885NPC1 1392/4885RAB9A 2646/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.