Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.54 |
| ▸ | PLK1 | P53350 | 1/20 | 0.53 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 3/20 | 0.52 |
| ▸ | PPARD | Q03181 | 3/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.52 |
| ▸ | PPARA | Q07869 | 2/20 | 0.52 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.51 |
| ▸ | ACLY | P53396 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 4/20 | 0.49 |
| ▸ | HSPH1 | Q92598 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lithium Ion SCHEMBL7037271 | 0.89 | PPARG (0.48) | IGF2BP2ACMSDPPARGPPARDNR1H4 | |
| SCHEMBL7033993 | 0.82 | NR1H4 (0.53) | IGF2BP2ACMSDPPARGPPARDNR1H4 | |
| SCHEMBL7040190 | 0.81 | PPARG (0.56) | IGF2BP2PPARGPPARDNR1H4PPARA | |
| SCHEMBL2273085 | 0.79 | ACLY (0.60) | ACMSDSERPINE1ACLYPTGER4HDAC2 | |
| SCHEMBL2267918 | 0.77 | ACLY (0.74) | IGF2BP2PPARGPPARDNR1H4PPARA | |
| SCHEMBL7038115 | 0.77 | IGF2BP2 (0.50) | IGF2BP2PLK1ACMSDPPARGPPARD | |
| SCHEMBL7038149 | 0.76 | IGF2BP2 (0.49) | IGF2BP2PLK1ACMSDPPARGPPARD | |
| SCHEMBL30542002 | 0.76 | AGXT (0.64) | ACMSDDHODHMGLL | |
| SCHEMBL2244213 | 0.76 | AGXT (0.64) | ACMSDDHODHMGLL | |
| SCHEMBL7038634 | 0.76 | ACLY (0.56) | IGF2BP2PLK1SERPINE1ACLYHDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | claimed |
| US-20030073862-A1 | Compounds | BIOVITRUM AB (SE) | 2003-04-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030073862-A1 | Compounds | PPARG, PPARA, PPARD | IGF2BP2 1574/4885PLK1 4580/4885ACMSD 2296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.