SCHEMBL7038339

SCHEMBL7038339

CCOC(=O)CC1(O)c2cc(O[Si](C)(C)C(C)(C)C)c(F)cc2CC1C

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 1/20 0.37
AKR1B1 P15121 1/20 0.31
MLYCD O95822 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7035560 0.72 DRD2 (0.42) DRD2
SCHEMBL31476429 0.68
SCHEMBL24237006 0.65 TTR (0.51) DRD2
SCHEMBL9098580 0.62 DRD2 (0.43) DRD2
SCHEMBL7568908 0.62 AKR1B1 (0.41) DRD2AKR1B1
SCHEMBL22032598 0.62 DRD2 (0.53) DRD2
SCHEMBL1363327 0.60 DRD2 (0.48) DRD2
SCHEMBL4513355 0.60 DRD2 (0.39) DRD2
SCHEMBL10487451 0.60 AKR1B1 (0.71) AKR1B1
SCHEMBL10487484 0.59 AKR1B1 (0.73) AKR1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003003012-A1 IDENTIFICATION OF INTERACTING MOLECULES MEDIMOLECULAR PTY. LTD. (AU) 2003-01-09 WO disclosed