Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.30 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7032828 | 0.80 | NR4A1 (0.35) | SMN1; SMN2BRD4NLRP3LMNA | |
| SCHEMBL6932963 | 0.75 | GAA (0.40) | LMNA | |
| SCHEMBL7041034 | 0.73 | TK2 (0.32) | SMN1; SMN2BRD4LMNA | |
| SCHEMBL7038339 | 0.72 | DRD2 (0.37) | DRD2 | |
| SCHEMBL6936638 | 0.72 | HSP90AB1 (0.36) | SMN1; SMN2NLRP3LMNA | |
| SCHEMBL11663434 | 0.71 | LMNA (0.37) | STING1LMNA | |
| SCHEMBL1363327 | 0.69 | DRD2 (0.48) | DRD2SMN1; SMN2LMNA | |
| SCHEMBL10452032 | 0.68 | ALDH1A1 (0.41) | DRD2CYP11B1CYP11B2SMN1; SMN2 | |
| SCHEMBL23218907 | 0.67 | DRD2 (0.49) | DRD2SMN1; SMN2LMNA | |
| SCHEMBL8686339 | 0.67 | PPARG (0.36) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003003012-A1 | IDENTIFICATION OF INTERACTING MOLECULES | MEDIMOLECULAR PTY. LTD. (AU) | 2003-01-09 | — | — | WO | disclosed |