Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.43 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.42 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6720862 | 0.86 | KMT2A (0.45) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL22991498 | 0.82 | KMT2A (0.43) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL4269670 | 0.81 | MEN1 (0.63) | KMT2AMEN1NR4A2NR4A1NR4A3 | |
| SCHEMBL15416567 | 0.80 | MEN1 (0.53) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL17854065 | 0.79 | TPMT (0.58) | HSD17B10TDP1ALDH1A1LMNAMAPK1 | |
| SCHEMBL9328838 | 0.75 | KMT2A (0.65) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL18646100 | 0.74 | ALDH1A1 (0.55) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| Hydrochloric Acid SCHEMBL9488543 | 0.74 | KMT2A (0.63) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL30929673 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL7427343 | 0.73 | ALDH1A1 (0.55) | KMT2AMEN1HTTGFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |