Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | EYA3 | Q99504 | 2/20 | 0.39 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7038375 | 0.86 | KMT2A (0.56) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL6723591 | 0.82 | THRA (0.46) | KMT2AALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL6725779 | 0.79 | KMT2A (0.64) | KMT2AMEN1ALDH1A1LMNASLC6A2 | |
| SCHEMBL22991498 | 0.77 | KMT2A (0.43) | KMT2AMEN1HTTGFERHSD17B10 | |
| SCHEMBL6723918 | 0.76 | ALDH1A1 (0.47) | KMT2AALDH1A1LMNASLC6A2SLC6A3 | |
| SCHEMBL6721180 | 0.74 | ALDH1A1 (0.43) | KMT2AMEN1ALDH1A1LMNASLC6A2 | |
| SCHEMBL6731605 | 0.74 | ALDH1A1 (0.45) | KMT2AHTTALDH1A1LMNASLC6A2 | |
| SCHEMBL7753141 | 0.73 | LMNA (0.40) | KMT2AMEN1HTTALDH1A1LMNA | |
| SCHEMBL6721207 | 0.73 | GABRA1 (0.59) | KMT2AMEN1ALDH1A1LMNASLC6A2 | |
| SCHEMBL30929673 | 0.72 | ALDH1A1 (0.55) | KMT2AMEN1HTTGFERHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6677473-B1 | TREATMENT, PREVENTION OR AMELIORATION OF ONE OR MORE SYMPTOMS OF THROMBOTIC DISORDERS, UNSTABLE ANGINA OR CANCER | CORVAS INTERNATIONAL INC | 2004-01-13 | — | — | US | disclosed |
| WO-2003009871-A2 | INHIBITORS OF PLASMINOGEN ACTIVATOR INHIBITOR FOR DECREASING BODY MASS | GENSET S.A. (FR) | 2003-02-06 | — | — | WO | disclosed |
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |